UniProt Q60751
Insulin-like growth factor 1 receptor (Q60751)
Insulin-like growth factor 1 receptor (UniProt Q60751), EC 2.7.10.1: 3 experimental structures and 1 predicted model on GenesisL1, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q60751
- Protein
- Insulin-like growth factor 1 receptor
- EC
- 2.7.10.1
- Experimental structures
- 3
- Predicted models
- 1
- Pockets
- 16 · 1 record with a druggable one
Structures
4 records of Q60751 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6PYH | Cryo-EM structure of full-length IGF1R-IGF1 complex. Only the extracellular region of the complex… | electron microscopy | A, D | — | — |
| 6PYH | Cryo-EM structure of full-length IGF1R-IGF1 complex. only the extracellular region of the complex… | electron microscopy | A, D | — | — |
| 8EYR | Cryo-EM structure of two IGF1 bound full-length mouse IGF1R mutant (four glycine residues inserted… | electron microscopy | B, A | — | 16 (best 0.82) |
| Q60751 | AlphaFold monomer V2.0 prediction for insulin-like growth factor 1 receptor (Q60751) | predicted | A | — | — |
Experiment against prediction
- 6PYH chain A against the predicted model Q60751: TM-score 0.66, RMSD 4.32 Å
- 6PYH chain A against the predicted model Q60751: TM-score 0.66, RMSD 4.32 Å
- 6PYH chain D against the predicted model Q60751: TM-score 0.47, RMSD 6.08 Å
- 6PYH chain D against the predicted model Q60751: TM-score 0.47, RMSD 6.08 Å
- 8EYR chain A against the predicted model Q60751: TM-score 0.46, RMSD 5.00 Å
- 8EYR chain B against the predicted model Q60751: TM-score 0.46, RMSD 4.93 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.