UniProt Q5VWK5
Interleukin-23 receptor (Q5VWK5)
Interleukin-23 receptor (UniProt Q5VWK5): 5 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5VWK5
- Protein
- Interleukin-23 receptor
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 10 · 3 records with a druggable one
Structures
6 records of Q5VWK5 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5MZV | IL-23:IL-23R:Nb22E11 complex | x-ray diffraction | C | NAG, CL | — |
| 5MZV | Il-23:IL-23R:NB22E11 complex | x-ray diffraction | C | NAG, CL | — |
| 6WDQ | IL23/IL23R/IL12Rb1 signaling complex | x-ray diffraction | C | NAG | 2 (best 0.83) |
| 6WDQ | IL23/IL23R/IL12RB1 signaling complex | x-ray diffraction | C | NAG | — |
| 8OE4 | Cryo-EM structure of a pre-dimerized human IL-23 complete extracellular signaling complex. | electron microscopy | C | NAG | 2 (best 0.80) |
| Q5VWK5 | AlphaFold monomer V2.0 prediction for interleukin-23 receptor (Q5VWK5) | predicted | A | — | 6 (best 0.51) |
Ligands
Experiment against prediction
- 5MZV chain C against the predicted model Q5VWK5: TM-score 0.99, RMSD 0.70 Å
- 5MZV chain C against the predicted model Q5VWK5: TM-score 0.99, RMSD 0.70 Å
- 8OE4 chain C against the predicted model Q5VWK5: TM-score 0.95, RMSD 1.51 Å
- 6WDQ chain C against the predicted model Q5VWK5: TM-score 0.94, RMSD 1.69 Å
- 6WDQ chain C against the predicted model Q5VWK5: TM-score 0.94, RMSD 1.69 Å
- 8OE4 chain C against the predicted model P0DP23: TM-score 0.18, RMSD 5.39 Å
Elsewhere
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