UniProt Q5VVQ6
Ubiquitin thioesterase OTU1 (Q5VVQ6)
Ubiquitin thioesterase OTU1 (UniProt Q5VVQ6), EC 3.4.19.12: 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 19 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q5VVQ6
- Protein
- Ubiquitin thioesterase OTU1
- EC
- 3.4.19.12
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 19 · 4 records with a druggable one
Structures
7 records of Q5VVQ6 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4BOQ | Structure of OTUD2 OTU domain | x-ray diffraction | A | — | — |
| 4BOQ | Structure of OTUD2 otu domain | x-ray diffraction | A | — | — |
| 4BOS | Structure of OTUD2 OTU domain in complex with Ubiquitin K11-linked peptide | x-ray diffraction | A, B | NO3, MG | 4 (best 0.68) |
| 4BOS | Structure of OTUD2 otu domain in complex with ubiquitin K11-linked peptide | x-ray diffraction | A, B | NO3, MG | 4 (best 0.68) |
| 4BOZ | Structure of OTUD2 OTU domain in complex with K11-linked di ubiquitin | x-ray diffraction | A, D | — | 5 (best 0.61) |
| 4BOZ | Structure of OTUD2 otu domain in complex with K11-linked di ubiquitin | x-ray diffraction | A, D | — | 5 (best 0.61) |
| Q5VVQ6 | AlphaFold monomer V2.0 prediction for ubiquitin thioesterase OTU1 (Q5VVQ6) | predicted | A | — | 1 (best 0.33) |
Ligands
Experiment against prediction
- 4BOZ chain A against the predicted model Q5VVQ6: TM-score 0.99, RMSD 0.48 Å
- 4BOZ chain A against the predicted model Q5VVQ6: TM-score 0.99, RMSD 0.48 Å
- 4BOZ chain D against the predicted model Q5VVQ6: TM-score 0.99, RMSD 0.60 Å
- 4BOZ chain D against the predicted model Q5VVQ6: TM-score 0.99, RMSD 0.60 Å
- 4BOS chain A against the predicted model Q5VVQ6: TM-score 0.98, RMSD 0.79 Å
- 4BOS chain A against the predicted model Q5VVQ6: TM-score 0.98, RMSD 0.79 Å
- 4BOQ chain A against the predicted model Q5VVQ6: TM-score 0.95, RMSD 1.53 Å
- 4BOQ chain A against the predicted model Q5VVQ6: TM-score 0.95, RMSD 1.53 Å
Elsewhere
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