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UniProt Q5UNP6

6-deoxyerythronolide B synthase (Q5UNP6)

6-deoxyerythronolide B synthase (UniProt Q5UNP6), EC 2.3.1.94: 15 experimental structures on GenesisL1, 2 ligands bound, 66 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q5UNP6
Protein
6-deoxyerythronolide B synthase
EC
2.3.1.94
Experimental structures
15
Predicted models
0
Ligands
2
Pockets
66 · 5 records with a druggable one

Structures

15 records of Q5UNP6 in the MolNFT archive: 15 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6W7SKetoreductase from module 1 of the 6-deoxyerythronolide B synthase (KR1) in complex with antibody…x-ray diffractionA—8 (best 0.71)
6W7SKetoreductase from module 1 of the 6-deoxyerythronolide B synthase (KR1) in complex with antibody…x-ray diffractionA——
6WH9Ketoreductase from module 1 of the 6-deoxyerythronolide B synthase (KR1) in complex with antibody…x-ray diffractionG, D, ASO4—
7M7E6-Deoxyerythronolide B synthase (DEBS) hybrid module (M3/1) in complex with antibody fragment 1B2electron microscopyB, A—19 (best 0.86)
7M7E6-deoxyerythronolide B synthase (debs) hybrid module (M3/1) in complex with antibody fragment 1B2electron microscopyB, A——
7M7F6-deoxyerythronolide B synthase (debs) module 1 in complex with antibody fragment 1B2: state 1electron microscopyB, APN7—
7M7G6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 2electron microscopyA, B——
7M7G6-deoxyerythronolide B synthase (debs) module 1 in complex with antibody fragment 1B2: state 2electron microscopyA, B——
7M7H6-deoxyerythronolide B synthase (debs) module 1 in complex with antibody fragment 1B2: state 1'electron microscopyB, A——
7M7I6-deoxyerythronolide B synthase (debs) module 1 in complex with antibody fragment 1B2 (te-free)electron microscopyB, APN7—
7M7J6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: "turnstile…electron microscopyB, A——
7M7J6-deoxyerythronolide B synthase (debs) module 1 in complex with antibody fragment 1B2: "turnstile…electron microscopyB, A——
8EE1KS-AT didomain from module 2 of the 6-deoxyerythronolide B synthase in complex with antibody…x-ray diffractionA, D—18 (best 0.71)
8TJNCrosslinked 6-deoxyerythronolide B synthase (DEBS) Module 1 in complex with antibody fragment 1B2…electron microscopyB, A—18 (best 0.88)
8TKOKS-AT core of 6-deoxyerythronolide B synthase (DEBS) Module 3 crosslinked with its translocation…electron microscopyC—3 (best 0.87)

Ligands

  • PN7 · N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy) butanoyl]-N-(2-sulfanylethyl)-beta-alaninamide · in 2 records
  • SO4 · Sulfate ion · in 1 record

Elsewhere

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