UniProt Q5U5Q9
Ubiquitin interaction motif-containing protein 1 (Q5U5Q9)
Ubiquitin interaction motif-containing protein 1 (UniProt Q5U5Q9): 4 experimental structures and 1 predicted model on GenesisL1, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5U5Q9
- Protein
- Ubiquitin interaction motif-containing protein 1
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 15 · 3 records with a druggable one
Structures
5 records of Q5U5Q9 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3A1Q | Crystal structure of the mouse RAP80 UIMs in complex with Lys63-linked di-ubiquitin | x-ray diffraction | C, F | — | 4 (best 0.59) |
| 3A1Q | Crystal structure of the mouse RAP80 uims in complex with LYS63-linked di-ubiquitin | x-ray diffraction | C, F | — | 4 (best 0.59) |
| 6GVW | Crystal structure of the BRCA1-A complex | x-ray diffraction | E, J | — | 5 (best 0.67) |
| 6GVW | Crystal structure of the BRCA1-a complex | x-ray diffraction | E, J | — | — |
| Q5U5Q9 | AlphaFold monomer V2.0 prediction for BRCA1-a complex subunit RAP80 (Q5U5Q9) | predicted | A | — | 2 (best 0.28) |
Experiment against prediction
- 3A1Q chain C against the predicted model Q5U5Q9: TM-score 0.80, RMSD 1.30 Å
- 3A1Q chain C against the predicted model Q5U5Q9: TM-score 0.80, RMSD 1.30 Å
- 6GVW chain E against the predicted model Q5U5Q9: TM-score 0.48, RMSD 2.58 Å
- 6GVW chain E against the predicted model Q5U5Q9: TM-score 0.48, RMSD 2.58 Å
Elsewhere
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