UniProt Q5TC82
Roquin-1 (Q5TC82)
Roquin-1 (UniProt Q5TC82), EC 2.3.2.27: 11 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5TC82
- Protein
- Roquin-1
- EC
- 2.3.2.27
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 9 · 1 record with a druggable one
Structures
12 records of Q5TC82 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3X1O | Crystal structure of the ROQ domain of human Roquin | x-ray diffraction | A, B | — | — |
| 3X1O | Crystal structure of the roq domain of human roquin | x-ray diffraction | A, B | — | — |
| 4QIK | Crystal structure of the ROQ domain of human Roquin in complex with the TNF23 RNA duplex | x-ray diffraction | A, B | — | — |
| 4QIK | Crystal structure of the roq domain of human roquin in complex with the TNF23 RNA duplex | x-ray diffraction | A, B | — | — |
| 4QIL | Crystal structure of the ROQ domain of human Roquin in complex with the Hmg19 stem-loop RNA | x-ray diffraction | A, B | — | — |
| 4QIL | Crystal structure of the roq domain of human roquin in complex with the HMG19 stem-loop RNA | x-ray diffraction | A, B | — | — |
| 4ULW | Crystal structure of the ROQ-domain of human ROQUIN1 | x-ray diffraction | A, B | — | — |
| 4ULW | Crystal structure of the roq-domain of human ROQUIN1 | x-ray diffraction | A, B | — | — |
| 4YWQ | Crystal structure of the ROQ domain of human Roquin-1 | x-ray diffraction | A, B | — | — |
| 4YWQ | Crystal structure of the roq domain of human roquin-1 | x-ray diffraction | A, B | — | — |
| 8RHS | Structure of the ZnF domain from human Roquin-1 | solution nmr | A | — | 1 (best 0.29) |
| Q5TC82 | AlphaFold monomer V2.0 prediction for roquin-1 (Q5TC82) | predicted | A | — | 8 (best 0.64) |
Experiment against prediction
- 3X1O chain A against the predicted model Q5TC82: TM-score 0.99, RMSD 0.57 Å
- 3X1O chain A against the predicted model Q5TC82: TM-score 0.99, RMSD 0.57 Å
- 4ULW chain A against the predicted model Q5TC82: TM-score 0.98, RMSD 0.98 Å
- 4ULW chain A against the predicted model Q5TC82: TM-score 0.98, RMSD 0.98 Å
- 4YWQ chain B against the predicted model Q5TC82: TM-score 0.98, RMSD 0.96 Å
- 4YWQ chain B against the predicted model Q5TC82: TM-score 0.98, RMSD 0.96 Å
- 3X1O chain B against the predicted model Q5TC82: TM-score 0.98, RMSD 1.04 Å
- 3X1O chain B against the predicted model Q5TC82: TM-score 0.98, RMSD 1.04 Å
- 4YWQ chain A against the predicted model Q5TC82: TM-score 0.98, RMSD 1.09 Å
- 4YWQ chain A against the predicted model Q5TC82: TM-score 0.98, RMSD 1.09 Å
Elsewhere
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