UniProt Q5TBB1
Ribonuclease H2 subunit B (Q5TBB1)
Ribonuclease H2 subunit B (UniProt Q5TBB1), EC 3.1.26.4: 7 experimental structures and 1 predicted model on GenesisL1, 76 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5TBB1
- Protein
- Ribonuclease H2 subunit B
- EC
- 3.1.26.4
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 76 · 6 records with a druggable one
Structures
8 records of Q5TBB1 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3P56 | The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme… | x-ray diffraction | B, E | — | 11 (best 0.72) |
| 3P56 | The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme… | x-ray diffraction | B, E | — | 11 (best 0.72) |
| 3P87 | Structure of human PCNA bound to RNASEH2B PIP box peptide | x-ray diffraction | G, H, I, J, K, L | — | 8 (best 0.64) |
| 3P87 | Structure of human PCNA bound to RNASEH2B pip box peptide | x-ray diffraction | G, H, I, J, K, L | — | 8 (best 0.64) |
| 3PUF | Crystal structure of human RNase H2 complex | x-ray diffraction | B, E, H, K, N, Q | — | 16 (best 0.79) |
| 3PUF | Crystal structure of human RNase H2 complex | x-ray diffraction | B, E, H, K, N, Q | — | 16 (best 0.79) |
| 8YJZ | Structure of the human endogenous PCNA-FEN1-RNase H2 complex - State D | electron microscopy | G | — | 3 (best 0.50) |
| Q5TBB1 | AlphaFold monomer V2.0 prediction for ribonuclease H2 subunit B (Q5TBB1) | predicted | A | — | 3 (best 0.38) |
Experiment against prediction
- 3PUF chain B against the predicted model Q5TBB1: TM-score 0.99, RMSD 0.63 Å
- 3PUF chain B against the predicted model Q5TBB1: TM-score 0.99, RMSD 0.63 Å
- 3PUF chain E against the predicted model Q5TBB1: TM-score 0.98, RMSD 0.66 Å
- 3PUF chain E against the predicted model Q5TBB1: TM-score 0.98, RMSD 0.66 Å
- 3PUF chain H against the predicted model Q5TBB1: TM-score 0.98, RMSD 0.74 Å
- 3PUF chain H against the predicted model Q5TBB1: TM-score 0.98, RMSD 0.74 Å
- 3PUF chain N against the predicted model Q5TBB1: TM-score 0.98, RMSD 0.70 Å
- 3PUF chain N against the predicted model Q5TBB1: TM-score 0.98, RMSD 0.70 Å
- 3PUF chain K against the predicted model Q5TBB1: TM-score 0.98, RMSD 0.82 Å
- 3PUF chain K against the predicted model Q5TBB1: TM-score 0.98, RMSD 0.82 Å
Elsewhere
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