UniProt Q5T6V5
Queuosine salvage protein (Q5T6V5)
Queuosine salvage protein (UniProt Q5T6V5): 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5T6V5
- Protein
- Queuosine salvage protein
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 18 · 3 records with a druggable one
Structures
3 records of Q5T6V5 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7UGK | Crystal structure of the human queuine salvage enzyme DUF2419, wild-type apo form | x-ray diffraction | A, B | — | 7 (best 0.81) |
| 8DL3 | Crystal structure of the human queuine salvage enzyme DUF2419, complexed with queuine | x-ray diffraction | A, B | QEI | 8 (best 0.79) |
| Q5T6V5 | AlphaFold monomer V2.0 prediction for queuosine salvage protein (Q5T6V5) | predicted | A | — | 3 (best 0.76) |
Ligands
- QEI · 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one · in 1 record
Experiment against prediction
- 7UGK chain A against the predicted model Q5T6V5: TM-score 0.99, RMSD 0.54 Å
- 8DL3 chain A against the predicted model Q5T6V5: TM-score 0.99, RMSD 0.56 Å
- 8DL3 chain B against the predicted model Q5T6V5: TM-score 0.98, RMSD 0.76 Å
- 7UGK chain B against the predicted model Q5T6V5: TM-score 0.98, RMSD 0.77 Å
Elsewhere
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