UniProt Q5T6F0
DDB1- and CUL4-associated factor 12 (Q5T6F0)
DDB1- and CUL4-associated factor 12 (UniProt Q5T6F0): 6 experimental structures and 1 predicted model on GenesisL1, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5T6F0
- Protein
- DDB1- and CUL4-associated factor 12
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 14 · 2 records with a druggable one
Structures
7 records of Q5T6F0 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3I7P | Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR40A | x-ray diffraction | B | — | — |
| 3I7P | Crystal structure of DDB1 in complex with the H-box motif of WDR40A | x-ray diffraction | B | — | — |
| 8AJM | Structure of human DDB1-DCAF12 in complex with the C-terminus of CCT5 | electron microscopy | B | — | — |
| 8AJN | Structure of the human DDB1-DCAF12 complex | electron microscopy | B | — | — |
| 8AJO | Negative-stain electron microscopy structure of DDB1-DCAF12-CCT5 | electron microscopy | B | — | 7 (best 0.85) |
| 8T9A | CryoEM structure of human DDB1-DCAF12 in complex with MAGEA3 | electron microscopy | B | — | 7 (best 0.79) |
| Q5T6F0 | AlphaFold monomer V2.0 prediction for DDB1- and CUL4-associated factor 12 (Q5T6F0) | predicted | A | — | — |
Experiment against prediction
- 8AJM chain B against the predicted model Q5T6F0: TM-score 0.94, RMSD 1.65 Å
- 8AJN chain B against the predicted model Q5T6F0: TM-score 0.94, RMSD 1.90 Å
- 8T9A chain B against the predicted model Q5T6F0: TM-score 0.94, RMSD 1.74 Å
- 8AJO chain B against the predicted model Q5T6F0: TM-score 0.92, RMSD 2.14 Å
- 3I7P chain B against the predicted model Q5T6F0: TM-score 0.55, RMSD 1.59 Å
- 3I7P chain B against the predicted model Q5T6F0: TM-score 0.55, RMSD 1.59 Å
Elsewhere
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