UniProt Q5SJA1
L-lactate dehydrogenase (Q5SJA1)
L-lactate dehydrogenase (UniProt Q5SJA1): 14 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5SJA1
- Protein
- L-lactate dehydrogenase
- Experimental structures
- 14
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
15 records of Q5SJA1 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2E37 | Structure of TT0471 protein from Thermus thermophilus | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 2E37 | Structure of TT0471 protein from thermus thermophilus | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 2V6M | Crystal structure of lactate dehydrogenase from Thermus Thermophilus HB8 (Apo form) | x-ray diffraction | A, B, C, D | — | — |
| 2V6M | Crystal structure of lactate dehydrogenase from thermus thermophilus HB8 (apo form) | x-ray diffraction | A, B, C, D | — | — |
| 2V7P | Crystal structure of lactate dehydrogenase from Thermus Thermophilus HB8 (Holo form) | x-ray diffraction | A, B, C, D | — | — |
| 2V7P | Crystal structure of lactate dehydrogenase from thermus thermophilus HB8 (holo form) | x-ray diffraction | A, B, C, D | — | — |
| 2XXB | Penta-mutant of Thermus thermophilus lactate dehydrogenase, complex with AMP | x-ray diffraction | A, B | — | — |
| 2XXB | Penta-mutant of thermus thermophilus lactate dehydrogenase, complex with AMP | x-ray diffraction | A, B | — | — |
| 2XXJ | Penta mutant of lactate dehydrogenase from Thermus thermophilus, ternary complex | x-ray diffraction | A, B, C, D | — | — |
| 2XXJ | Penta mutant of lactate dehydrogenase from thermus thermophilus, ternary complex | x-ray diffraction | A, B, C, D | — | — |
| 3ZZN | 5-Mutant (R79W, R151A, E279A, E299A,E313A) Lactate-Dehydrogenase from Thermus thermophillus | x-ray diffraction | A, B, C, D | — | — |
| 3ZZN | 5-mutant (R79W, R151A, E279A, E299A,E313A) lactate-dehydrogenase from thermus thermophillus | x-ray diffraction | A, B, C, D | — | — |
| 4A73 | Single point mutant of thermus thermophilus lactate dehydrogenase | x-ray diffraction | A, B, C, D | — | — |
| 4A73 | Single point mutant of thermus thermophilus lactate dehydrogenase | x-ray diffraction | A, B, C, D | — | — |
| Q5SJA1 | AlphaFold monomer V2.0 prediction for L-lactate dehydrogenase (Q5SJA1) | predicted | A | — | 2 (best 0.65) |
Experiment against prediction
- 2V6M chain B against the predicted model Q5SJA1: TM-score 0.99, RMSD 0.50 Å
- 2V6M chain B against the predicted model Q5SJA1: TM-score 0.99, RMSD 0.50 Å
- 2V6M chain A against the predicted model Q5SJA1: TM-score 0.99, RMSD 0.52 Å
- 2V6M chain A against the predicted model Q5SJA1: TM-score 0.99, RMSD 0.52 Å
- 3ZZN chain A against the predicted model Q5SJA1: TM-score 0.99, RMSD 0.54 Å
- 3ZZN chain A against the predicted model Q5SJA1: TM-score 0.99, RMSD 0.54 Å
- 2XXB chain A against the predicted model Q5SJA1: TM-score 0.99, RMSD 0.55 Å
- 2XXB chain A against the predicted model Q5SJA1: TM-score 0.99, RMSD 0.55 Å
- 2E37 chain D against the predicted model Q5SJA1: TM-score 0.99, RMSD 0.60 Å
- 2E37 chain D against the predicted model Q5SJA1: TM-score 0.99, RMSD 0.60 Å
Elsewhere
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