UniProt Q5SIY4
Q5SIY4
Q5SIY4 (UniProt Q5SIY4): 37 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5SIY4
- Experimental structures
- 37
- Predicted models
- 1
Structures
38 records of Q5SIY4 in the MolNFT archive: 37 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1DPZ | Structure of modified 3-isopropylmalate dehydrogenase at the C-terminus, HD711 | x-ray diffraction | A, B | — | — |
| 1DPZ | Structure of modified 3-isopropylmalate dehydrogenase at the C- terminus, HD711 | x-ray diffraction | A, B | — | — |
| 1DR0 | Structure of modified 3-isopropylmalate dehydrogenase at the C-terminus, HD708 | x-ray diffraction | A, B | — | — |
| 1DR0 | Structure of modified 3-isopropylmalate dehydrogenase at the C- terminus, HD708 | x-ray diffraction | A, B | — | — |
| 1DR8 | Structure of modified 3-isopropylmalate dehydrogenase at the C-terminus, HD177 | x-ray diffraction | A, B | — | — |
| 1DR8 | Structure of modified 3-isopropylmalate dehydrogenase at the C- terminus, HD177 | x-ray diffraction | A, B | — | — |
| 1G2U | The structure of the mutant, A172V, of 3-isopropylmalate dehydrogenase from thermus thermophilus… | x-ray diffraction | A | — | — |
| 1G2U | The structure of the mutant, A172V, of 3-isopropylmalate dehydrogenase from thermus thermophilus… | x-ray diffraction | A | — | — |
| 1GC8 | The crystal structure of thermus thermophilus 3-isopropylmalate dehydrogenase mutated at 172TH from… | x-ray diffraction | A, B | — | — |
| 1GC8 | The crystal structure of thermus thermophilus 3-isopropylmalate dehydrogenase mutated at 172TH from… | x-ray diffraction | A, B | — | — |
| 1GC9 | The crystal structure of thermus thermophilus 3-isopropylmalate dehydrogenase mutated at 172TH from… | x-ray diffraction | A | — | — |
| 1GC9 | The crystal structure of thermus thermophilus 3-isopropylmalate dehydrogenase mutated at 172TH from… | x-ray diffraction | A | — | — |
| 1HEX | Structure of 3-isopropylmalate dehydrogenase in complex with NAD+: ligand-induced loop-closing and… | x-ray diffraction | A | — | — |
| 1HEX | Structure of 3-isopropylmalate dehydrogenase in complex with NAD+: ligand-induced loop-closing and… | x-ray diffraction | A | — | — |
| 1IPD | Three-dimensional structure of a highly thermostable enzyme, 3-isopropylmalate dehydrogenase of… | x-ray diffraction | A | — | — |
| 1IPD | Three-dimensional structure of a highly thermostable enzyme, 3- isopropylmalate dehydrogenase of… | x-ray diffraction | A | — | — |
| 1OSI | Structure of 3-isopropylmalate dehydrogenase | x-ray diffraction | A, B, C, D | — | — |
| 1OSI | Structure of 3-isopropylmalate dehydrogenase | x-ray diffraction | A, B, C, D | — | — |
| 1OSJ | Structure of 3-isopropylmalate dehydrogenase | x-ray diffraction | A, B | — | — |
| 1OSJ | Structure of 3-isopropylmalate dehydrogenase | x-ray diffraction | A, B | — | — |
| 1XAA | 3-isopropylmalate dehydrogenase, low temperature (100K) structure | x-ray diffraction | A | — | — |
| 1XAA | 3-isopropylmalate dehydrogenase, low temperature (100K) structure | x-ray diffraction | A | — | — |
| 1XAB | 3-isopropylmalate dehydrogenase, low temperature (150K) structure | x-ray diffraction | A | — | — |
| 1XAB | 3-isopropylmalate dehydrogenase, low temperature (150K) structure | x-ray diffraction | A | — | — |
| 2Y3Z | Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - apo enzyme | x-ray diffraction | A | — | — |
| 2Y3Z | Structure of isopropylmalate dehydrogenase from thermus thermophilus - apo enzyme | x-ray diffraction | A | — | — |
| 2Y40 | Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - complex with Mn | x-ray diffraction | A, B | — | — |
| 2Y40 | Structure of isopropylmalate dehydrogenase from thermus thermophilus - complex with mn | x-ray diffraction | A, B | — | — |
| 2Y41 | Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - complex with IPM and MN | x-ray diffraction | A, B | — | — |
| 2Y41 | Structure of isopropylmalate dehydrogenase from thermus thermophilus - complex with ipm and mn | x-ray diffraction | A, B | — | — |
| 2Y42 | Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - complex with NADH and Mn | x-ray diffraction | A, B, C, D | — | — |
| 2Y42 | Structure of isopropylmalate dehydrogenase from thermus thermophilus - complex with NADH and mn | x-ray diffraction | A, B, C, D | — | — |
| 2ZTW | Structure of 3-isopropylmalate dehydrogenase in complex with the inhibitor and NAD+ | x-ray diffraction | A | — | — |
| 2ZTW | Structure of 3-isopropylmalate dehydrogenase in complex with the inhibitor and NAD+ | x-ray diffraction | A | — | — |
| 4F7I | Structure of Isopropylmalate dehydrogenase from Thermus thermophilus in complex with IPM, Mn and… | x-ray diffraction | A, B, C, D | — | — |
| 4F7I | Structure of isopropylmalate dehydrogenase from thermus thermophilus in complex with ipm, mn and… | x-ray diffraction | A, B, C, D | — | — |
| 4WUO | Structure of the E270A mutant isopropylmalate dehydrogenase from thermus thermophilus in complex… | x-ray diffraction | A, B | — | — |
| Q5SIY4 | AlphaFold monomer V2.0 prediction for 3-isopropylmalate dehydrogenase (Q5SIY4) | predicted | A | — | — |
Experiment against prediction
- 2Y42 chain B against the predicted model Q5SIY4: TM-score 0.98, RMSD 0.54 Å
- 2Y42 chain B against the predicted model Q5SIY4: TM-score 0.98, RMSD 0.54 Å
- 1DPZ chain B against the predicted model Q5SIY4: TM-score 0.97, RMSD 1.17 Å
- 1DPZ chain B against the predicted model Q5SIY4: TM-score 0.97, RMSD 1.17 Å
- 2Y41 chain A against the predicted model Q5SIY4: TM-score 0.97, RMSD 1.16 Å
- 2Y41 chain A against the predicted model Q5SIY4: TM-score 0.97, RMSD 1.16 Å
- 1DPZ chain A against the predicted model Q5SIY4: TM-score 0.97, RMSD 1.23 Å
- 1DPZ chain A against the predicted model Q5SIY4: TM-score 0.97, RMSD 1.23 Å
- 1DR8 chain A against the predicted model Q5SIY4: TM-score 0.97, RMSD 1.29 Å
- 1DR8 chain A against the predicted model Q5SIY4: TM-score 0.97, RMSD 1.29 Å
Elsewhere
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