UniProt Q5SHZ1
50S ribosomal protein L25 (Q5SHZ1)
50S ribosomal protein L25 (UniProt Q5SHZ1): 165 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 28 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5SHZ1
- Protein
- 50S ribosomal protein L25
- Experimental structures
- 165
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 28 · 24 records with a druggable one
Structures
166 records of Q5SHZ1 in the MolNFT archive: 165 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1VVJ | Crystal Structure of Frameshift Suppressor tRNA SufA6 bound to Codon CCC-G on the Ribosome | x-ray diffraction | RZ, YZ | — | — |
| 1VY4 | Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond… | x-ray diffraction | BZ, DZ | — | — |
| 1VY5 | Crystal structure of the Thermus thermophilus 70S ribosome in the post-catalysis state of peptide… | x-ray diffraction | BZ, DZ | — | — |
| 1VY6 | Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond… | x-ray diffraction | BZ, DZ | — | — |
| 1VY7 | Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond… | x-ray diffraction | BZ, DZ | — | — |
| 4L47 | Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCC-U on the Ribosome | x-ray diffraction | RZ, YZ | — | — |
| 4L71 | Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCC-A on the Ribosome | x-ray diffraction | RZ, YZ | — | — |
| 4LEL | Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCG-G on the Ribosome | x-ray diffraction | RZ, YZ | — | — |
| 4LFZ | Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCC-U in the Absence of… | x-ray diffraction | RZ, YZ | — | — |
| 4LNT | Crystal Structure of tRNA Proline (CGG) Bound to Codon CCC-U on the Ribosome | x-ray diffraction | RZ, YZ | — | — |
| 4LSK | Crystal Structure of tRNA Proline (CGG) Bound to Codon CCG-G on the Ribosome | x-ray diffraction | RZ, YZ | — | — |
| 4LT8 | Crystal Structure of tRNA Proline (CGG) Bound to Codon CCC-G on the Ribosome | x-ray diffraction | RZ, YZ | — | — |
| 4P6F | Crystal structure of the peptolide 12C bound to bacterial ribosome | x-ray diffraction | RZ, YZ | — | — |
| 4P70 | Crystal Structure of Unmodified tRNA Proline (CGG) Bound to Codon CCG on the Ribosome | x-ray diffraction | RZ, YZ | — | — |
| 4TUA | Crystal structure of ASL-Thr bound to Codon ACC-A on the Ribosome | x-ray diffraction | RZ, YZ | — | — |
| 4TUB | Crystal structure of tRNA-Thr bound to Codon ACC-C on the Ribosome | x-ray diffraction | RZ, YZ | — | — |
| 4TUC | Crystal structure of ASL-SufJ bound to Codon ACC-A on the Ribosome | x-ray diffraction | RZ, YZ | — | — |
| 4TUD | Crystal structure of ASL-SufJ bound to Codon ACC-C on the Ribosome | x-ray diffraction | RZ, YZ | — | — |
| 4TUE | Crystal structure of ASL-SufJ bound to Codon ACC-U on the Ribosome | x-ray diffraction | RZ, YZ | — | — |
| 4V4X | Crystal structure of the 70S Thermus thermophilus ribosome showing how the 16S 3'-end mimicks mRNA… | x-ray diffraction | BY | — | — |
| 4V4Y | Crystal structure of the 70S Thermus thermophilus ribosome with translocated and rotated… | x-ray diffraction | BY | — | — |
| 4V4Z | 70S Thermus thermophilous ribosome functional complex with mRNA and E- and P-site tRNAs at 4.5A. | x-ray diffraction | BY | — | — |
| 4V51 | Structure of the Thermus thermophilus 70S ribosome complexed with mRNA, tRNA and paromomycin | x-ray diffraction | BZ, DZ | — | — |
| 4V5A | Structure of the Ribosome Recycling Factor bound to the Thermus thermophilus 70S ribosome with… | x-ray diffraction | BZ, DZ | — | — |
| 4V5C | Structure of the Thermus thermophilus 70S ribosome in complex with mRNA, paromomycin, acylated… | x-ray diffraction | BZ, DZ | — | — |
| 4V5D | Structure of the Thermus thermophilus 70S ribosome in complex with mRNA, paromomycin, acylated A… | x-ray diffraction | BZ, DZ | — | — |
| 4V5E | Insights into translational termination from the structure of RF2 bound to the ribosome | x-ray diffraction | BZ, DZ | — | — |
| 4V5F | The structure of the ribosome with elongation factor G trapped in the post-translocational state | x-ray diffraction | BZ, DZ | — | — |
| 4V5G | The crystal structure of the 70S ribosome bound to EF-Tu and tRNA | x-ray diffraction | BZ, DZ | — | — |
| 4V5J | Structure of the 70S ribosome bound to Release factor 2 and a substrate analog provides insights… | x-ray diffraction | BZ, DZ | — | — |
| 4V5K | Structure of cytotoxic domain of colicin E3 bound to the 70S ribosome | x-ray diffraction | BZ, DZ | — | — |
| 4V5L | The structure of EF-Tu and aminoacyl-tRNA bound to the 70S ribosome with a GTP analog | x-ray diffraction | BZ | — | — |
| 4V5M | tRNA tranlocation on the 70S ribosome: the pre-translocational translocation intermediate TI(PRE) | electron microscopy | BZ | — | — |
| 4V5N | tRNA translocation on the 70S ribosome: the post- translocational translocation intermediate… | electron microscopy | BZ | — | — |
| 4V5P | The crystal structure of EF-Tu and A9C-tRNA-Trp bound to a near- cognate codon on the 70S ribosome | x-ray diffraction | BZ, DZ | — | — |
| 4V5Q | The crystal structure of EF-Tu and G24A-tRNA-Trp bound to a near- cognate codon on the 70S ribosome | x-ray diffraction | BZ, DZ | — | — |
| 4V5R | The crystal structure of EF-Tu and Trp-tRNA-Trp bound to a cognate codon on the 70S ribosome. | x-ray diffraction | BZ, DZ | — | — |
| 4V5S | The crystal structure of EF-Tu and G24A-tRNA-Trp bound to a cognate codon on the 70S ribosome. | x-ray diffraction | BZ, DZ | — | — |
| 4V68 | T. thermophilus 70S ribosome in complex with mRNA, tRNAs and EF-Tu.GDP.kirromycin ternary complex… | electron microscopy | BZ | — | — |
| 4V6A | Structure of EF-P bound to the 70S ribosome. | x-ray diffraction | BZ, DZ | — | — |
| 4V6F | Elongation complex of the 70S ribosome with three tRNAs and mRNA. | x-ray diffraction | AV, DV | — | — |
| 4V6G | Initiation complex of 70S ribosome with two tRNAs and mRNA. | x-ray diffraction | BV, DV | — | — |
| 4V7J | Structure of RelE nuclease bound to the 70S ribosome (precleavage state) | x-ray diffraction | AZ, BZ | — | — |
| 4V7K | Structure of RelE nuclease bound to the 70S ribosome (postcleavage state) | x-ray diffraction | AZ, BZ | — | — |
| 4V7L | The structures of viomycin bound to the 70S ribosome. | x-ray diffraction | BZ, DZ | — | — |
| 4V7M | The structures of Capreomycin bound to the 70S ribosome. | x-ray diffraction | BZ, DZ | — | — |
| 4V7W | Structure of the Thermus thermophilus ribosome complexed with chloramphenicol. | x-ray diffraction | BZ, DZ | — | — |
| 4V7X | Structure of the Thermus thermophilus ribosome complexed with erythromycin. | x-ray diffraction | BZ, DZ | — | — |
| 4V7Y | Structure of the Thermus thermophilus 70S ribosome complexed with azithromycin. | x-ray diffraction | BZ, DZ | — | — |
| 4V7Z | Structure of the Thermus thermophilus 70S ribosome complexed with telithromycin. | x-ray diffraction | BZ, DZ | — | — |
| 4V87 | Crystal structure analysis of ribosomal decoding. | x-ray diffraction | AV, DV | — | — |
| 4V8A | The structure of thermorubin in complex with the 70S ribosome from Thermus thermophilus. | x-ray diffraction | AZ, BZ | — | — |
| 4V8B | Crystal structure analysis of ribosomal decoding (near-cognate tRNA-leu complex). | x-ray diffraction | BV, DV | — | — |
| 4V8C | Crystal structure analysis of ribosomal decoding (near-cognate tRNA-leu complex with paromomycin). | x-ray diffraction | AV, BV | — | — |
| 4V8D | Structure analysis of ribosomal decoding (cognate tRNA-tyr complex). | x-ray diffraction | BV, DV | — | — |
| 4V8E | Crystal structure analysis of ribosomal decoding (near-cognate tRNA-tyr complex). | x-ray diffraction | AV, CV | — | — |
| 4V8F | Crystal structure analysis of ribosomal decoding (near-cognate tRNA-ttyr complex with paromomycin). | x-ray diffraction | AV, DV | — | — |
| 4V8G | Crystal structure of RMF bound to the 70S ribosome. | x-ray diffraction | BZ, DZ | — | — |
| 4V8H | Crystal structure of HPF bound to the 70S ribosome. | x-ray diffraction | BZ, DZ | — | — |
| 4V8I | Crystal structure of YfiA bound to the 70S ribosome. | x-ray diffraction | BZ, DZ | — | — |
106 records more on the page itself.
Ligands
Experiment against prediction
- 4W2F chain BZ against the predicted model Q5SHZ1: TM-score 0.98, RMSD 0.80 Å
- 4Z3S chain 1Z against the predicted model Q5SHZ1: TM-score 0.97, RMSD 0.79 Å
- 7U2J chain 1Z against the predicted model Q5SHZ1: TM-score 0.97, RMSD 0.84 Å
- 5NDK chain D5 against the predicted model Q5SHZ1: TM-score 0.97, RMSD 0.75 Å
- 9D0J chain 1Z against the predicted model Q5SHZ1: TM-score 0.97, RMSD 0.90 Å
- 7RQ8 chain 1Z against the predicted model Q5SHZ1: TM-score 0.97, RMSD 0.93 Å
- 5EL4 chain H8 against the predicted model Q5SHZ1: TM-score 0.97, RMSD 0.83 Å
- 6OF1 chain 1Z against the predicted model Q5SHZ1: TM-score 0.97, RMSD 0.93 Å
- 7U2I chain 1Z against the predicted model Q5SHZ1: TM-score 0.97, RMSD 0.89 Å
- 8UD7 chain 1Z against the predicted model Q5SHZ1: TM-score 0.97, RMSD 0.96 Å
Elsewhere
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