UniProt Q5SGX1

Phenylalanyl-tRNA synthetase (Q5SGX1)

Phenylalanyl-tRNA synthetase (UniProt Q5SGX1), EC 6.1.1.20: 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 84 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…

UniProt: Q5SGX1
Protein: Phenylalanyl-tRNA synthetase
EC: 6.1.1.20
Experimental structures: 6
Predicted models: 1
Ligands: 3
Pockets: 84 · 7 records with a druggable one

Structures

7 records of Q5SGX1 in the MolNFT archive: 6 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
1EIY	The crystal structure of phenylalanyl-tRNA synthetase from thermus thermophilus complexed with…	x-ray diffraction	C	—	7 (best 0.76)
1EIY	The crystal structure of phenylalanyl-tRNA synthetase from thermus thermophilus complexed with…	x-ray diffraction	C	—	7 (best 0.76)
1JJC	Crystal structure at 2.6A resolution of phenylalanyl-tRNA synthetase complexed with…	x-ray diffraction	B	MN, SO4	16 (best 0.71)
1JJC	Crystal structure at 2.6A resolution of phenylalanyl-tRNA synthetase complexed with…	x-ray diffraction	B	MN, SO4	16 (best 0.71)
1PYS	Phenylalanyl-tRNA synthetase from thermus thermophilus	x-ray diffraction	B	MG	14 (best 0.70)
1PYS	Phenylalanyl-tRNA synthetase from thermus thermophilus	x-ray diffraction	B	MG	14 (best 0.70)
Q5SGX1	AlphaFold monomer V2.0 prediction for phenylalanine--tRNA ligase beta subunit (Q5SGX1)	predicted	A	—	10 (best 0.68)

Ligands

MG · Magnesium ion · in 2 records
MN · Manganese (II) ion · in 2 records
SO4 · Sulfate ion · in 2 records

Experiment against prediction

1JJC chain B against the predicted model Q5SGX1: TM-score 0.97, RMSD 1.61 Å
1JJC chain B against the predicted model Q5SGX1: TM-score 0.97, RMSD 1.61 Å
1PYS chain B against the predicted model Q5SGX1: TM-score 0.97, RMSD 1.61 Å
1PYS chain B against the predicted model Q5SGX1: TM-score 0.97, RMSD 1.61 Å

Elsewhere

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