UniProt Q5QGZ9
C-type lectin domain family 12 member A (Q5QGZ9)
C-type lectin domain family 12 member A (UniProt Q5QGZ9): 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5QGZ9
- Protein
- C-type lectin domain family 12 member A
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 6 · 2 records with a druggable one
Structures
4 records of Q5QGZ9 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8JAH | Crystal structure of human CLEC12A C-type lectin domain | x-ray diffraction | A, B | SO4, K | 1 (best 0.79) |
| 8W8T | Crystal structure of human CLEC12A CRD | x-ray diffraction | A, B | SO4 | 1 (best 0.77) |
| 8W9J | Crystal structure of human CLEC12A ectodomain complexed with 50C1 Fab | x-ray diffraction | C, D | — | 4 (best 0.47) |
| Q5QGZ9 | AlphaFold monomer V2.0 prediction for C-type lectin domain family 12 member a (Q5QGZ9) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8W9J chain D against the predicted model Q5QGZ9: TM-score 0.98, RMSD 0.78 Å
- 8W8T chain A against the predicted model Q5QGZ9: TM-score 0.97, RMSD 0.76 Å
- 8JAH chain A against the predicted model Q5QGZ9: TM-score 0.97, RMSD 0.76 Å
- 8JAH chain B against the predicted model Q5QGZ9: TM-score 0.97, RMSD 0.77 Å
- 8W8T chain B against the predicted model Q5QGZ9: TM-score 0.97, RMSD 0.83 Å
- 8W9J chain C against the predicted model Q5QGZ9: TM-score 0.94, RMSD 1.23 Å
Elsewhere
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