UniProt Q5JE31
DNA-directed RNA polymerase subunit H (Q5JE31)
DNA-directed RNA polymerase subunit H (UniProt Q5JE31), EC 2.7.7.6: 10 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5JE31
- Protein
- DNA-directed RNA polymerase subunit H
- EC
- 2.7.7.6
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 9 · 4 records with a druggable one
Structures
11 records of Q5JE31 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4QIW | Crystal structure of euryarchaeal RNA polymerase from Thermococcus kodakarensis | x-ray diffraction | H, S | — | — |
| 4QIW | Crystal structure of euryarchaeal RNA polymerase from thermococcus kodakarensis | x-ray diffraction | H, S | — | — |
| 6KF3 | Cryo-EM structure of Thermococcus kodakarensis RNA polymerase | electron microscopy | H | — | — |
| 6KF3 | Cryo-EM structure of thermococcus kodakarensis RNA polymerase | electron microscopy | H | — | — |
| 6KF4 | Cryo-EM structure of Thermococcus kodakarensis RNA polymerase | electron microscopy | H | — | 3 (best 0.80) |
| 6KF4 | Cryo-EM structure of thermococcus kodakarensis RNA polymerase | electron microscopy | H | — | — |
| 6KF9 | Cryo-EM structure of Thermococcus kodakarensis RNA polymerase | electron microscopy | H | — | 3 (best 0.75) |
| 6KF9 | Cryo-EM structure of thermococcus kodakarensis RNA polymerase | electron microscopy | H | — | — |
| 9BCT | Cryo-EM structure of Thermococcus kodakarensis FttA-dependent transcription pre-termination complex… | electron microscopy | H | — | 1 (best 0.72) |
| 9BCU | Cryo-EM structure of Thermococcus kodakarensis FttA-dependent transcription pre-termination complex… | electron microscopy | H | — | 2 (best 0.80) |
| Q5JE31 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit H (Q5JE31) | predicted | A | — | — |
Experiment against prediction
- 9BCU chain H against the predicted model Q5JE31: TM-score 0.99, RMSD 0.37 Å
- 9BCT chain H against the predicted model Q5JE31: TM-score 0.99, RMSD 0.38 Å
- 4QIW chain H against the predicted model Q5JE31: TM-score 0.94, RMSD 0.93 Å
- 4QIW chain H against the predicted model Q5JE31: TM-score 0.94, RMSD 0.93 Å
- 6KF3 chain H against the predicted model Q5JE31: TM-score 0.93, RMSD 0.90 Å
- 6KF3 chain H against the predicted model Q5JE31: TM-score 0.93, RMSD 0.90 Å
- 6KF9 chain H against the predicted model Q5JE31: TM-score 0.92, RMSD 0.93 Å
- 6KF9 chain H against the predicted model Q5JE31: TM-score 0.92, RMSD 0.93 Å
- 6KF4 chain H against the predicted model Q5JE31: TM-score 0.92, RMSD 0.92 Å
- 6KF4 chain H against the predicted model Q5JE31: TM-score 0.92, RMSD 0.92 Å
Elsewhere
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