UniProt Q5IXS3
Primase D5 (Q5IXS3)
Primase D5 (UniProt Q5IXS3): 16 experimental structures on GenesisL1, 7 ligands bound, 320 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q5IXS3
- Protein
- Primase D5
- Experimental structures
- 16
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 320 · 16 records with a druggable one
Structures
16 records of Q5IXS3 in the MolNFT archive: 16 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8HWA | D5 ATP-ADP-Apo-ssDNA IS1 | electron microscopy | A, B, C, D, E, F, K | ATP, MG, ADP | 20 (best 0.84) |
| 8HWB | D5 ATP-ADP-Apo-ssDNA IS2 | electron microscopy | A, B, C, D, E, F, K | ATP, MG, ADP | 20 (best 0.84) |
| 8HWC | Cryo-EM Structure of D5 Apo | electron microscopy | E, F, D, C, B, A | — | 20 (best 0.70) |
| 8HWD | Cryo-EM Structure of D5 ADP form | electron microscopy | A, F, D, E, C, B | ADP | 20 (best 0.84) |
| 8HWE | Cryo-EM Structure of D5 ATP-ADP form | electron microscopy | D, C, F, A, E, B | ATP, MG, ADP | 20 (best 0.86) |
| 8HWF | Cryo-EM Structure of D5 ADP-ssDNA form | electron microscopy | C, B, F, E, D, A | ADP, MG | 20 (best 0.86) |
| 8HWG | D5 ATPrS-ADP-ssDNA form | electron microscopy | C, B, D, A, F, E | AGS, MG, ADP | 20 (best 0.82) |
| 8HWH | Cryo-EM Structure of D5 Apo-ssDNA form | electron microscopy | A, B, C, D, E, F | — | 20 (best 0.84) |
| 8WGY | MPOX E5 hexamer AMP-PNP and ssDNA bound form with clear primase domain | electron microscopy | B, E, D, F, C, A | ANP, MG, ZN | 20 (best 0.87) |
| 8WGZ | MPOX E5 double hexamer ssDNA bound conformation | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L | — | 20 (best 0.85) |
| 8WH0 | MPOX E5 hexamer ssDNA and AMP-PNP bound conformation | electron microscopy | A, B, C, D, E, F | MG, ANP | 20 (best 0.87) |
| 8WH2 | MPOX E5 hexamer 2ATP, 2ADP, and ssDNA binding comformation | electron microscopy | A, B, C, D, E, F | ATP, MG, ADP | 20 (best 0.86) |
| 8WH3 | MPOX E5 hexamer apo form | electron microscopy | A, B, C, D, E, F | — | 20 (best 0.78) |
| 8WH6 | MPOX E5 hexamer ADP and ssDNA bound and clear primase domain conformation | electron microscopy | A, B, C, D, E, F | ADP, ZN | 20 (best 0.88) |
| 8XJ6 | The Cryo-EM structure of MPXV E5 apo conformation | electron microscopy | A, B, C, D, E, F | ANP, AN2, ZN | 20 (best 0.81) |
| 8XJ7 | The Cryo-EM structure of MPXV E5 in complex with DNA | electron microscopy | A, B, C, D, E, F | ANP, MG | 20 (best 0.87) |
Ligands
- MG · Magnesium ion · in 9 records
- ADP · Adenosine-5'-diphosphate · in 8 records
- ANP · Phosphoaminophosphonic acid-adenylate ester · in 4 records
- ATP · Adenosine-5'-triphosphate · in 4 records
- ZN · Zinc ion · in 3 records
- AGS · Phosphothiophosphoric acid-adenylate ester · in 1 record
- AN2 · Amp phosphoramidate · in 1 record
Elsewhere
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