UniProt Q5FWF5
N-acetyltransferase ESCO1 (Q5FWF5)
N-acetyltransferase ESCO1 (UniProt Q5FWF5), EC 2.3.1.-: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5FWF5
- Protein
- N-acetyltransferase ESCO1
- EC
- 2.3.1.-
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 2 · 1 record with a druggable one
Structures
5 records of Q5FWF5 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4MXE | Human ESCO1 (Eco1/Ctf7 ortholog), acetyltransferase domain in complex with acetyl-CoA | x-ray diffraction | A, B | — | — |
| 4MXE | Human ESCO1 (ECO1/CTF7 ortholog), acetyltransferase domain in complex with acetyl-CoA | x-ray diffraction | A, B | — | — |
| 5T53 | Molecular basis for cohesin acetylation by establishment of sister chromatid cohesion… | x-ray diffraction | A | ACO, ZN | 2 (best 0.67) |
| 5T53 | Molecular basis for cohesin acetylation by establishment of sister chromatid cohesion… | x-ray diffraction | A | ACO, ZN | — |
| Q5FWF5 | AlphaFold monomer V2.0 prediction for N-acetyltransferase ESCO1 (Q5FWF5) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4MXE chain A against the predicted model Q5FWF5: TM-score 0.90, RMSD 1.41 Å
- 4MXE chain A against the predicted model Q5FWF5: TM-score 0.90, RMSD 1.41 Å
- 5T53 chain A against the predicted model Q5FWF5: TM-score 0.89, RMSD 1.86 Å
- 5T53 chain A against the predicted model Q5FWF5: TM-score 0.89, RMSD 1.86 Å
- 4MXE chain B against the predicted model Q5FWF5: TM-score 0.88, RMSD 1.36 Å
- 4MXE chain B against the predicted model Q5FWF5: TM-score 0.88, RMSD 1.36 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.