UniProt Q5EG47
5'-AMP-activated protein kinase catalytic subunit alpha-1 (Q5EG47)
5'-AMP-activated protein kinase catalytic subunit alpha-1 (UniProt Q5EG47), EC 2.7.11.1: 2 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 20 pockets. Binding sites, druggability and experiment…
- UniProt
- Q5EG47
- Protein
- 5'-AMP-activated protein kinase catalytic subunit alpha-1
- EC
- 2.7.11.1
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 20 · 2 records with a druggable one
Structures
3 records of Q5EG47 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5UFU | Structure of AMPK bound to activator | x-ray diffraction | A | STU, 85V, CL, SO4 | 10 (best 0.69) |
| 5UFU | Structure of ampk bound to activator | x-ray diffraction | A | STU, 85V, CL, SO4 | 10 (best 0.69) |
| Q5EG47 | AlphaFold monomer V2.0 prediction for 5'-AMP-activated protein kinase catalytic subunit alpha-1… | predicted | A | — | — |
Ligands
Experiment against prediction
- 5UFU chain A against the predicted model P54645: TM-score 0.99, RMSD 0.88 Å
- 5UFU chain A against the predicted model P54645: TM-score 0.99, RMSD 0.88 Å
- 5UFU chain A against the predicted model Q5EG47: TM-score 0.99, RMSD 0.88 Å
- 5UFU chain A against the predicted model Q5EG47: TM-score 0.99, RMSD 0.88 Å
Elsewhere
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