UniProt Q5D1E7
Ribonuclease ZC3H12A (Q5D1E7)
Ribonuclease ZC3H12A (UniProt Q5D1E7), EC 3.1.-.-: 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5D1E7
- Protein
- Ribonuclease ZC3H12A
- EC
- 3.1.-.-
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 10 · 2 records with a druggable one
Structures
11 records of Q5D1E7 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2N5J | Regnase-1 N-terminal domain | solution nmr | A | — | — |
| 2N5J | Regnase-1 N-terminal domain | solution nmr | A | — | — |
| 2N5K | Regnase-1 Zinc finger domain | solution nmr | A | — | — |
| 2N5K | Regnase-1 zinc finger domain | solution nmr | A | — | — |
| 2N5L | Regnase-1 C-terminal domain | solution nmr | A | — | — |
| 2N5L | Regnase-1 C-terminal domain | solution nmr | A | — | — |
| 5H9V | Crystal structure of Regnase PIN domain, form I | x-ray diffraction | A, B, C, D | NA | 6 (best 0.61) |
| 5H9V | Crystal structure of regnase pin domain, form I | x-ray diffraction | A, B, C, D | — | — |
| 5H9W | Crystal structure of Regnase PIN domain, form II | x-ray diffraction | A, B | NA | 3 (best 0.59) |
| 5H9W | Crystal structure of regnase pin domain, form II | x-ray diffraction | A, B | — | — |
| Q5D1E7 | AlphaFold monomer V2.0 prediction for endoribonuclease ZC3H12A (Q5D1E7) | predicted | A | — | 1 (best 0.25) |
Ligands
- NA · Sodium ion · in 2 records
Experiment against prediction
- 5H9V chain C against the predicted model Q5D1E7: TM-score 1.00, RMSD 0.33 Å
- 5H9V chain C against the predicted model Q5D1E7: TM-score 1.00, RMSD 0.33 Å
- 5H9V chain B against the predicted model Q5D1E7: TM-score 0.99, RMSD 0.36 Å
- 5H9V chain B against the predicted model Q5D1E7: TM-score 0.99, RMSD 0.36 Å
- 5H9W chain B against the predicted model Q5D1E7: TM-score 0.99, RMSD 0.38 Å
- 5H9V chain D against the predicted model Q5D1E7: TM-score 0.99, RMSD 0.39 Å
- 5H9W chain A against the predicted model Q5D1E7: TM-score 0.98, RMSD 0.74 Å
- 5H9W chain A against the predicted model Q5D1E7: TM-score 0.98, RMSD 0.74 Å
- 5H9V chain A against the predicted model Q5D1E7: TM-score 0.98, RMSD 0.75 Å
- 5H9V chain A against the predicted model Q5D1E7: TM-score 0.98, RMSD 0.75 Å
Elsewhere
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