UniProt Q58970
GMP synthase [glutamine-hydrolyzing] subunit A (Q58970)
GMP synthase [glutamine-hydrolyzing] subunit A (UniProt Q58970), EC 6.3.5.2: 12 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 25 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q58970
- Protein
- GMP synthase [glutamine-hydrolyzing] subunit A
- EC
- 6.3.5.2
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 25 · 2 records with a druggable one
Structures
13 records of Q58970 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2LXN | Solution NMR structure of glutamine amido transferase subunit of gaunosine monophosphate synthetase… | solution nmr | A | — | — |
| 2LXN | Solution NMR structure of glutamine amido transferase subunit of gaunosine monophosphate synthetase… | solution nmr | A | — | — |
| 7D40 | Crystal structure of GATase subunit of Methanocaldococcus jannaschii GMP synthetase | x-ray diffraction | A, B | — | 3 (best 0.44) |
| 7D40 | Crystal structure of gatase subunit of methanocaldococcus jannaschii gmp synthetase | x-ray diffraction | A, B | SNN | — |
| 7D95 | Crystal structure of acivicin-bound GATase subunit of Methanocaldococcus jannaschii GMP synthetase | x-ray diffraction | A, B | — | 1 (best 0.42) |
| 7D95 | Crystal structure of acivicin-bound gatase subunit of methanocaldococcus jannaschii gmp synthetase | x-ray diffraction | A, B | SNN | — |
| 7D96 | Crystal structure of D110G mutant of GATase subunit of Methanocaldococcus jannaschii GMP synthetase | x-ray diffraction | A | — | 1 (best 0.39) |
| 7D96 | Crystal structure of D110G mutant of gatase subunit of methanocaldococcus jannaschii gmp synthetase | x-ray diffraction | A | — | — |
| 7D97 | Crystal structure of N109P mutant of GATase subunit of Methanocaldococcus jannaschii GMP synthetase | x-ray diffraction | A, B, C, D | — | 11 (best 0.51) |
| 7D97 | Crystal structure of N109P mutant of gatase subunit of methanocaldococcus jannaschii gmp synthetase | x-ray diffraction | A, B, C, D | — | — |
| 7YC6 | Crystal structure of D110P mutant of GATase subunit of Methanocaldococcus jannaschii GMP synthetase | x-ray diffraction | A | ZN | 1 (best 0.34) |
| 8GR1 | Crystal structure of D110V/K151L mutant of GATase subunit of Methanocaldococcus jannaschii GMP… | x-ray diffraction | A, B, C, D | SO4 | 8 (best 0.83) |
| Q58970 | AlphaFold monomer V2.0 prediction for gmp synthase [glutamine- hydrolyzing] subunit a (Q58970) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7D95 chain B against the predicted model Q58970: TM-score 0.98, RMSD 0.71 Å
- 7D95 chain A against the predicted model Q58970: TM-score 0.98, RMSD 0.71 Å
- 7D95 chain B against the predicted model Q58970: TM-score 0.98, RMSD 0.71 Å
- 7D95 chain A against the predicted model Q58970: TM-score 0.98, RMSD 0.71 Å
- 7D40 chain B against the predicted model Q58970: TM-score 0.98, RMSD 0.71 Å
- 7D40 chain B against the predicted model Q58970: TM-score 0.98, RMSD 0.72 Å
- 7D40 chain A against the predicted model Q58970: TM-score 0.98, RMSD 0.72 Å
- 7D40 chain A against the predicted model Q58970: TM-score 0.98, RMSD 0.72 Å
- 7YC6 chain A against the predicted model Q58970: TM-score 0.98, RMSD 0.69 Å
- 7D96 chain A against the predicted model Q58970: TM-score 0.98, RMSD 0.74 Å
Elsewhere
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