UniProt Q58719
DNA double-strand break repair protein MRE11 (Q58719)
DNA double-strand break repair protein MRE11 (UniProt Q58719): 12 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q58719
- Protein
- DNA double-strand break repair protein MRE11
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 2 · 0 records with a druggable one
Structures
13 records of Q58719 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3AUZ | Crystal structure of Mre11 with manganese | x-ray diffraction | A | — | — |
| 3AUZ | Crystal structure of MRE11 with manganese | x-ray diffraction | A | — | — |
| 3AV0 | Crystal structure of Mre11-Rad50 bound to ATP S | x-ray diffraction | A | — | — |
| 3AV0 | Crystal structure of MRE11-RAD50 bound to ATP S | x-ray diffraction | A | — | — |
| 4TUG | Crystal structure of MjMre11-DNA2 complex | x-ray diffraction | C, A, B, D, E, F | — | — |
| 4TUG | Crystal structure of MJMRE11-DNA2 complex | x-ray diffraction | C, A, B, D, E, F | — | — |
| 4TUI | Crystal structure of MjMre11-DNA1 complex | x-ray diffraction | C, A, B, D, E, F | — | — |
| 4TUI | Crystal structure of MJMRE11-DNA1 complex | x-ray diffraction | C, A, B, D, E, F | — | — |
| 5DNY | Structure of the ATPrS-Mre11/Rad50-DNA complex | x-ray diffraction | A, C | MG | — |
| 5DNY | Structure of the atprs-MRE11/RAD50-DNA complex | x-ray diffraction | A, C | — | — |
| 5F3W | Structure of the ATPrS-Mre11/Rad50-DNA complex | x-ray diffraction | A, C | MG | — |
| 5F3W | Structure of the atprs-MRE11/RAD50-DNA complex | x-ray diffraction | A, C | — | — |
| Q58719 | AlphaFold monomer V2.0 prediction for DNA double-strand break repair protein MRE11 (Q58719) | predicted | A | — | 2 (best 0.30) |
Ligands
- MG · Magnesium ion · in 2 records
Experiment against prediction
- 4TUI chain C against the predicted model Q58719: TM-score 0.99, RMSD 0.75 Å
- 4TUI chain C against the predicted model Q58719: TM-score 0.99, RMSD 0.75 Å
- 4TUG chain B against the predicted model Q58719: TM-score 0.98, RMSD 0.84 Å
- 4TUG chain B against the predicted model Q58719: TM-score 0.98, RMSD 0.84 Å
- 4TUG chain D against the predicted model Q58719: TM-score 0.98, RMSD 0.77 Å
- 4TUG chain D against the predicted model Q58719: TM-score 0.98, RMSD 0.77 Å
- 4TUI chain B against the predicted model Q58719: TM-score 0.98, RMSD 0.88 Å
- 4TUI chain B against the predicted model Q58719: TM-score 0.98, RMSD 0.88 Å
- 4TUI chain D against the predicted model Q58719: TM-score 0.98, RMSD 0.83 Å
- 4TUI chain D against the predicted model Q58719: TM-score 0.98, RMSD 0.83 Å
Elsewhere
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