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UniProt Q54113

Penicillin binding protein 2 prime (Q54113)

Penicillin binding protein 2 prime (UniProt Q54113), EC 3.4.16.4: 11 experimental structures on GenesisL1, 6 ligands bound, 76 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q54113
Protein
Penicillin binding protein 2 prime
EC
3.4.16.4
Experimental structures
11
Predicted models
0
Ligands
6
Pockets
76 · 5 records with a druggable one

Structures

11 records of Q54113 in the MolNFT archive: 11 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
3ZFZCrystal structure of ceftaroline acyl-PBP2a from MRSA with non- covalently bound ceftaroline and…x-ray diffractionA, BCD, CL, AI8, 1W8, MUR16 (best 0.73)
3ZFZCrystal structure of ceftaroline acyl-PBP2A from mrsa with non- covalently bound ceftaroline and…x-ray diffractionA, B——
3ZG0Crystal structure of ceftaroline acyl-PBP2a from MRSA with non- covalently bound ceftaroline and…x-ray diffractionA, BAI8, CD, CL, 1W8, MUR14 (best 0.78)
3ZG0Crystal structure of ceftaroline acyl-PBP2A from mrsa with non- covalently bound ceftaroline and…x-ray diffractionA, B——
3ZG5Crystal structure of PBP2A from mrsa in complex with peptidoglycan analogue at allostericx-ray diffractionA, B——
4BL2Crystal structure of PBP2a clinical mutant E150K from MRSAx-ray diffractionA, BCD, CL15 (best 0.76)
4BL2Crystal structure of PBP2A clinical mutant E150K from mrsax-ray diffractionA, B——
4BL3Crystal structure of PBP2a clinical mutant N146K from MRSAx-ray diffractionA, BCD, CL, MUR15 (best 0.77)
4BL3Crystal structure of PBP2A clinical mutant N146K from mrsax-ray diffractionA, B——
4CJNCrystal structure of PBP2a from MRSA in complex with quinazoli ligandx-ray diffractionA, BCD, CL, MUR, QNZ16 (best 0.77)
4CJNCrystal structure of PBP2A from mrsa in complex with quinazolinone ligandx-ray diffractionA, B——

Ligands

  • CD · Cadmium ion · in 5 records
  • CL · Chloride ion · in 5 records
  • MUR · beta-muramic acid · in 4 records
  • 1W8 · Ceftaroline · in 2 records
  • AI8 · Ceftaroline, bound form · in 2 records
  • QNZ · (E)-3-(2-(4-cyanostyryl)-4-oxoquinazolin-3(4H)-yl)benzoic acid · in 1 record

Elsewhere

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