UniProt Q53Z42
HLA-A*02:01 alpha chain (Q53Z42)
HLA-A*02:01 alpha chain (UniProt Q53Z42): 17 experimental structures on GenesisL1, 4 ligands bound, 85 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q53Z42
- Protein
- HLA-A*02:01 alpha chain
- Experimental structures
- 17
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 85 · 15 records with a druggable one
Structures
17 records of Q53Z42 in the MolNFT archive: 17 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3TO2 | Structure of HLA-A*0201 complexed with peptide Md3-C9 derived from a clustering region of… | x-ray diffraction | A | — | 4 (best 0.68) |
| 3TO2 | Structure of HLA-A*0201 complexed with peptide MD3-C9 derived from a clustering region of… | x-ray diffraction | A | — | 4 (best 0.68) |
| 7RTD | SARS-CoV-2 Spike-derived peptide S269-277 (YLQPRTFLL) presented by HLA-A*02:01 | x-ray diffraction | A | — | 3 (best 0.67) |
| 7RTD | SARS-cov-2 spike-derived peptide S269-277 (ylqprtfll) presented by HLA-A*02:01 | x-ray diffraction | A | — | — |
| 7RTR | YLQ-SG3 TCR in complex with SARS-CoV-2 Spike-derived peptide S269-277 (YLQPRTFLL) presented by… | x-ray diffraction | A | NA | 6 (best 0.69) |
| 7RTR | Ylq-SG3 TCR in complex with SARS-cov-2 spike-derived peptide S269-277 (ylqprtfll) presented by… | x-ray diffraction | A | NA | — |
| 7U1R | SARS-CoV-2 Spike-derived peptide S1185-1193 K1191N mutant (RLNEVANNL) presented by HLA-A*02:01 | x-ray diffraction | A | CD, ZN, NA | 3 (best 0.68) |
| 7UM2 | SARS-CoV-2 Spike-derived peptide S417-425 K417T mutant (TIADYNYKL) presented by HLA-A*02:01 | x-ray diffraction | A | ZN, CD, NA | 4 (best 0.68) |
| 7UR1 | SARS-CoV-2 Spike-derived peptide S1215-1224 (YIWLGFIAGL) presented by HLA-A*02:01 | x-ray diffraction | A | — | 3 (best 0.69) |
| 8EB2 | Structure of HLA-A*02:01 in complex with NY-ESO-1 peptide and PA2.1 Fab | x-ray diffraction | A, D, G | — | 14 (best 0.77) |
| 8ESA | CryoEM structure of HLA-A2 bound to MAGEA4 (230-239) peptide | electron microscopy | A, B, C | — | 5 (best 0.66) |
| 8ESB | CryoEM structure of HLA-A2 bound to MAGEA8 (232-241) peptide | electron microscopy | A, B, C | — | 4 (best 0.67) |
| 8FU4 | HCMV US11 peptide binding to HLA-A*02:01 | x-ray diffraction | A | CD | 5 (best 0.68) |
| 8RBV | SARS-CoV-2 Spike-derived peptide S976-984 S982A mutant (VLNDILARL) presented by HLA-A*02:01 | x-ray diffraction | A | CD | 4 (best 0.69) |
| 8TBV | Human Class I MHC HLA-A2 in complex with sorting nexin 24 (127-135) neoantigen KLSHQLVLL | x-ray diffraction | A, D | — | 8 (best 0.76) |
| 8TBW | Human Class I MHC HLA-A2 in complex with sorting nexin 24 (127-135) peptide KLSHQPVLL | x-ray diffraction | A, D | NO3 | 10 (best 0.74) |
| 8U9G | Human Class I MHC HLA-A2 bound to sorting nexin 24 (127-135) neoantigen KLSHQLVLL | x-ray diffraction | A, D | — | 8 (best 0.75) |
Ligands
Elsewhere
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