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UniProt Q53Y41

Aromatic-L-amino-acid decarboxylase (Q53Y41)

Aromatic-L-amino-acid decarboxylase (UniProt Q53Y41), EC 4.1.1.28: 4 experimental structures on GenesisL1, 3 ligands bound, 26 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q53Y41
Protein
Aromatic-L-amino-acid decarboxylase
EC
4.1.1.28
Experimental structures
4
Predicted models
0
Ligands
3
Pockets
26 · 2 records with a druggable one

Structures

4 records of Q53Y41 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
3RBFCrystal structure of Human aromatic L-amino acid decarboxylase (AADC) in the apo formx-ray diffractionA, BPLP, CL9 (best 0.74)
3RBFCrystal structure of human aromatic L-amino acid decarboxylase (aadc) in the apo formx-ray diffractionA, BPLP, CL9 (best 0.74)
8OR9Human holo aromatic L-amino acid decarboxylase (AADC) native structure at physiological pHx-ray diffractionAPLP3 (best 0.44)
8ORAHuman holo aromatic L-amino acid decarboxylase (AADC) external aldimine with L-Dopa methylesterx-ray diffractionAPLP, W5I5 (best 0.47)

Ligands

  • PLP · Pyridoxal-5'-phosphate · in 4 records
  • CL · Chloride ion · in 2 records
  • W5I · methyl (2~{R})-2-azanyl-3-[3,4-bis(oxidanyl)phenyl]propanoate · in 1 record

Elsewhere

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