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UniProt Q53TN1

Dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) (Q53TN1)

Dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) (UniProt Q53TN1), EC 3.4.14.5: 4 experimental structures on GenesisL1, 5 ligands bound, 66 pockets. Binding sites, pockets, druggability and 3D structures in…

UniProt
Q53TN1
Protein
Dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2)
EC
3.4.14.5
Experimental structures
4
Predicted models
0
Ligands
5
Pockets
66 · 4 records with a druggable one

Structures

4 records of Q53TN1 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
2HHAThe structure of DPP4 in complex with an oxadiazole inhibitorx-ray diffractionA, BNAG, NDG, NA, 3TP17 (best 0.75)
2HHAThe structure of DPP4 in complex with an oxadiazole inhibitorx-ray diffractionA, BNAG, NDG, NA, 3TP17 (best 0.75)
3NOXCrystal structure of human DPP-IV in complex with Sa-(+)-(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-m…x-ray diffractionA, BNAG, 6A516 (best 0.75)
3NOXCrystal structure of human dpp-IV in complex with sa-(+)-(6…x-ray diffractionA, BNAG, 6A516 (best 0.75)

Ligands

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
  • 3TP · (2S,3S)-3-{3-[4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-oxo-1-pyrrolidin-1-ylbutan-2-amine · in 2 records
  • 6A5 · Sa-(+)-(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidin-2-yl)(morpholino)methanone · in 2 records
  • NA · Sodium ion · in 2 records
  • NDG · 2-acetamido-2-deoxy-alpha-D-glucopyranose · in 2 records

Elsewhere

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