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UniProt Q53FZ4

RAR-related orphan receptor C isoform a variant (Q53FZ4)

RAR-related orphan receptor C isoform a variant (UniProt Q53FZ4): 4 experimental structures on GenesisL1, 3 ligands bound, 16 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q53FZ4
Protein
RAR-related orphan receptor C isoform a variant
Experimental structures
4
Predicted models
0
Ligands
3
Pockets
16 · 4 records with a druggable one

Structures

4 records of Q53FZ4 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6O3ZCrystal structure of RORgt with 3-cyano-N-(3-{[(3S)-4-(cyclopentanecarbonyl)-3-methylpiperazin-1-yl]…x-ray diffractionALKY4 (best 0.83)
6O3ZCrystal structure of rorgt with 3-cyano-N-(3-{[(3S)-4…x-ray diffractionALKY4 (best 0.83)
7JTWCrystal structure of RORgt with compound (4R)-6-[(2,5-dichloro-3-{[(2R,4R)-1-(cyclopentanecarbonyl)…x-ray diffractionAVK4, SO44 (best 0.84)
7JTWCrystal structure of rorgt with compound (4R)-6-[(2,5-dichloro-3…x-ray diffractionAVK4, SO44 (best 0.84)

Ligands

  • LKY · 3-cyano-N-(3-{[(3S)-4-(cyclopentanecarbonyl)-3-methylpiperazin-1-yl]methyl}-5-fluoro-2-methylphenyl) benzamide · in 2 records
  • SO4 · Sulfate ion · in 2 records
  • VK4 · (4R)-6-[(2,5-dichloro-3-{[(2R,4R)-1-(cyclopentanecarbonyl)-2-methylpiperidin-4-yl]oxy}phenyl)amino]-6-oxo-4-phenylhexanoic acid · in 2 records

Elsewhere

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