UniProt Q53080
proteasome alpha-type subunit 1 (Q53080)
proteasome alpha-type subunit 1 (UniProt Q53080), EC 3.4.25.1: 6 experimental structures and 1 predicted model on GenesisL1, 93 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q53080
- Protein
- proteasome alpha-type subunit 1
- EC
- 3.4.25.1
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 93 · 6 records with a druggable one
Structures
7 records of Q53080 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1Q5Q | The Rhodococcus 20S proteasome | x-ray diffraction | A, B, C, D, E, F, G | — | 17 (best 0.78) |
| 1Q5Q | The rhodococcus 20S proteasome | x-ray diffraction | A, B, C, D, E, F, G | — | 17 (best 0.78) |
| 1Q5R | The Rhodococcus 20S proteasome with unprocessed pro-peptides | x-ray diffraction | A, B, C, D, E, F, G | — | 17 (best 0.81) |
| 1Q5R | The rhodococcus 20S proteasome with unprocessed pro-peptides | x-ray diffraction | A, B, C, D, E, F, G | — | 17 (best 0.81) |
| 2H6J | Crystal Structure of the Beta F145A Rhodococcus Proteasome | x-ray diffraction | A, B, C, D, E, F, G | — | 11 (best 0.83) |
| 2H6J | Crystal structure of the beta F145A rhodococcus proteasome | x-ray diffraction | A, B, C, D, E, F, G | — | 11 (best 0.83) |
| Q53080 | AlphaFold monomer V2.0 prediction for proteasome subunit alpha 1 (Q53080) | predicted | A | — | 3 (best 0.33) |
Experiment against prediction
- 1Q5Q chain A against the predicted model Q53080: TM-score 0.99, RMSD 0.46 Å
- 1Q5Q chain A against the predicted model Q53080: TM-score 0.99, RMSD 0.46 Å
- 1Q5R chain A against the predicted model Q53080: TM-score 0.99, RMSD 0.53 Å
- 1Q5R chain A against the predicted model Q53080: TM-score 0.99, RMSD 0.53 Å
- 2H6J chain A against the predicted model Q53080: TM-score 0.99, RMSD 0.60 Å
- 2H6J chain A against the predicted model Q53080: TM-score 0.99, RMSD 0.60 Å
Elsewhere
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