UniProt Q51792
Phenazine biosynthesis protein phzF (Q51792)
Phenazine biosynthesis protein phzF (UniProt Q51792), EC 5.3.3.17: 19 experimental structures and 1 predicted model on GenesisL1, 9 ligands bound, 12 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q51792
- Protein
- Phenazine biosynthesis protein phzF
- EC
- 5.3.3.17
- Experimental structures
- 19
- Predicted models
- 1
- Ligands
- 9
- Pockets
- 12 · 11 records with a druggable one
Structures
20 records of Q51792 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1T6K | Crystal structure of phzF from Pseudomonas fluorescens 2-79 | x-ray diffraction | A | SO4 | 1 (best 0.61) |
| 1T6K | Crystal structure of phzf from pseudomonas fluorescens 2-79 | x-ray diffraction | A | — | — |
| 1U1V | Structure and function of phenazine-biosynthesis protein PhzF from Pseudomonas fluorescens 2-79 | x-ray diffraction | A | SO4 | 2 (best 0.60) |
| 1U1V | Structure and function of phenazine-biosynthesis protein phzf from pseudomonas fluorescens 2-79 | x-ray diffraction | A | — | — |
| 1U1W | Structure and function of phenazine-biosynthesis protein PhzF from Pseudomonas fluorescens 2-79 | x-ray diffraction | A, B | 3HA | 1 (best 0.75) |
| 1U1W | Structure and function of phenazine-biosynthesis protein phzf from pseudomonas fluorescens 2-79 | x-ray diffraction | A, B | — | — |
| 1U1X | Structure and function of phenazine-biosynthesis protein PhzF from Pseudomonas fluorescens 2-79 | x-ray diffraction | A, B | HHA | 1 (best 0.76) |
| 1U1X | Structure and function of phenazine-biosynthesis protein phzf from pseudomonas fluorescens 2-79 | x-ray diffraction | A, B | — | — |
| 1XUA | Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens | x-ray diffraction | A, B | HHA | 1 (best 0.76) |
| 1XUA | Structure and function of the phenazine biosynthetic protein phzf from pseudomonas fluorescens | x-ray diffraction | A, B | — | — |
| 1XUB | Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens | x-ray diffraction | A | SO4 | 1 (best 0.61) |
| 1XUB | Structure and function of the phenazine biosynthetic protein phzf from pseudomonas fluorescens | x-ray diffraction | A | — | — |
| 5IWE | E45Q mutant of phenazine biosynthesis protein PhzF in complex with… | x-ray diffraction | A | W81 | — |
| 5IWE | E45Q mutant of phenazine biosynthesis protein phzf in complex with… | x-ray diffraction | A | — | — |
| 9F92 | Complex of phenazine biosynthesis enzyme PhzF with 2-amino-3-nitrobenzoic acid | x-ray diffraction | A | SO4, A1IAX | 1 (best 0.59) |
| 9F93 | Complex of phenazine biosynthesis enzyme PhzF with 2-amino-5-(4-fluorophenyl)benzoic acid | x-ray diffraction | A | A1IAV | 1 (best 0.58) |
| 9F94 | Complex of phenazine biosynthesis enzyme PhzF with 2-amino-5-(3-hydroxyphenyl)benzoic acid | x-ray diffraction | A | A1IAY | 1 (best 0.59) |
| 9F95 | Complex of phenazine biosynthesis enzyme PhzF with 2-amino-3-hydroxy-5-(3-hydroxyphenyl)benzoic acid | x-ray diffraction | A | A1IAU | 1 (best 0.56) |
| 9F96 | Complex of phenazine biosynthesis enzyme PhzF with 2-amino-3-ethoxybenzoic acid | x-ray diffraction | A | A1IAW | — |
| Q51792 | AlphaFold monomer V2.0 prediction for trans-2,3-dihydro-3-hydroxyanthranilate isomerase (Q51792) | predicted | A | — | 1 (best 0.58) |
Ligands
- SO4 · Sulfate ion · in 4 records
- HHA · (2S,3S)-trans-2,3-dihydro-3-hydroxyanthranilic acid · in 2 records
- 3HA · 3-hydroxyanthranilic acid · in 1 record
- A1IAU · 2-azanyl-5-(3-hydroxyphenyl)-3-oxidanyl-benzoic acid · in 1 record
- A1IAV · 2-azanyl-5-(4-fluorophenyl)benzoic acid · in 1 record
- A1IAW · 2-azanyl-3-ethoxy-benzoic acid · in 1 record
- A1IAX · 2-azanyl-3-nitro-benzoic acid · in 1 record
- A1IAY · 2-azanyl-5-(3-hydroxyphenyl)benzoic acid · in 1 record
- W81 · (5R,6R)-6-azaniumyl-5-ethoxycyclohexa-1,3-diene-1-carboxylate · in 1 record
Experiment against prediction
- 5IWE chain A against the predicted model Q51792: TM-score 0.99, RMSD 0.33 Å
- 5IWE chain A against the predicted model Q51792: TM-score 0.99, RMSD 0.33 Å
- 1XUB chain A against the predicted model Q51792: TM-score 1.00, RMSD 0.35 Å
- 1XUB chain A against the predicted model Q51792: TM-score 1.00, RMSD 0.35 Å
- 1U1V chain A against the predicted model Q51792: TM-score 1.00, RMSD 0.36 Å
- 1U1V chain A against the predicted model Q51792: TM-score 1.00, RMSD 0.36 Å
- 9F92 chain A against the predicted model Q51792: TM-score 1.00, RMSD 0.36 Å
- 9F94 chain A against the predicted model Q51792: TM-score 0.99, RMSD 0.39 Å
- 9F93 chain A against the predicted model Q51792: TM-score 1.00, RMSD 0.42 Å
- 1T6K chain A against the predicted model Q51792: TM-score 0.99, RMSD 0.44 Å
Elsewhere
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