UniProt Q51669
Glutathione-dependent formaldehyde-activating enzyme (Q51669)
Glutathione-dependent formaldehyde-activating enzyme (UniProt Q51669), EC 4.4.-.-: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 17 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q51669
- Protein
- Glutathione-dependent formaldehyde-activating enzyme
- EC
- 4.4.-.-
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 17 · 2 records with a druggable one
Structures
5 records of Q51669 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1X6M | Crystal structure of the glutathione-dependent formaldehyde-activating enzyme (Gfa) | x-ray diffraction | A, B, C, D | ZN, SO4 | 9 (best 0.67) |
| 1X6M | Crystal structure of the glutathione-dependent formaldehyde-activating enzyme (gfa) | x-ray diffraction | A, B, C, D | — | — |
| 1XA8 | Crystal Structure Analysis of Glutathione-dependent formaldehyde-activating enzyme (Gfa) | x-ray diffraction | A, B, C, D | ZN, SO4, GSH | 8 (best 0.70) |
| 1XA8 | Crystal structure analysis of glutathione-dependent formaldehyde- activating enzyme (gfa) | x-ray diffraction | A, B, C, D | — | — |
| Q51669 | AlphaFold monomer V2.0 prediction for glutathione-dependent formaldehyde-activating enzyme (Q51669) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1X6M chain C against the predicted model Q51669: TM-score 0.99, RMSD 0.39 Å
- 1X6M chain C against the predicted model Q51669: TM-score 0.99, RMSD 0.39 Å
- 1X6M chain D against the predicted model Q51669: TM-score 0.99, RMSD 0.39 Å
- 1X6M chain D against the predicted model Q51669: TM-score 0.99, RMSD 0.39 Å
- 1XA8 chain D against the predicted model Q51669: TM-score 0.99, RMSD 0.42 Å
- 1XA8 chain D against the predicted model Q51669: TM-score 0.99, RMSD 0.42 Å
- 1XA8 chain C against the predicted model Q51669: TM-score 0.99, RMSD 0.42 Å
- 1XA8 chain C against the predicted model Q51669: TM-score 0.99, RMSD 0.42 Å
- 1X6M chain B against the predicted model Q51669: TM-score 0.98, RMSD 0.50 Å
- 1X6M chain B against the predicted model Q51669: TM-score 0.98, RMSD 0.50 Å
Elsewhere
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