UniProt Q51426
Holliday junction ATP-dependent DNA helicase RuvB (Q51426)
Holliday junction ATP-dependent DNA helicase RuvB (UniProt Q51426), EC 3.6.4.12: 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 43 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q51426
- Protein
- Holliday junction ATP-dependent DNA helicase RuvB
- EC
- 3.6.4.12
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 43 · 6 records with a druggable one
Structures
6 records of Q51426 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6BLB | 1.88 Angstrom Resolution Crystal Structure Holliday Junction ATP-dependent DNA Helicase (RuvB) from… | x-ray diffraction | A | ADP | 3 (best 0.59) |
| 6BLB | 1.88 ångström resolution crystal structure holliday junction ATP- dependent DNA helicase (ruvb)… | x-ray diffraction | A | ADP | 3 (best 0.59) |
| 7X5B | Crystal structure of RuvB | x-ray diffraction | A | ADP | 4 (best 0.60) |
| 7X7P | CryoEM structure of dsDNA-RuvB-RuvA domain3 complex | electron microscopy | M, N, O, P | — | 20 (best 0.88) |
| 7X7Q | CryoEM structure of RuvA-RuvB-Holliday junction complex | electron microscopy | M, N, O, P | — | 11 (best 0.88) |
| Q51426 | AlphaFold monomer V2.0 prediction for holliday junction ATP-dependent DNA helicase ruvb (Q51426) | predicted | A | — | 2 (best 0.69) |
Ligands
- ADP · Adenosine-5'-diphosphate · in 3 records
Experiment against prediction
- 7X5B chain A against the predicted model Q51426: TM-score 0.95, RMSD 1.70 Å
- 6BLB chain A against the predicted model Q51426: TM-score 0.95, RMSD 1.72 Å
- 6BLB chain A against the predicted model Q51426: TM-score 0.95, RMSD 1.72 Å
- 7X7P chain O against the predicted model Q51426: TM-score 0.95, RMSD 1.64 Å
- 7X7Q chain O against the predicted model Q51426: TM-score 0.94, RMSD 1.68 Å
- 7X7P chain N against the predicted model Q51426: TM-score 0.91, RMSD 2.35 Å
- 7X7Q chain N against the predicted model Q51426: TM-score 0.91, RMSD 2.34 Å
- 7X7P chain M against the predicted model Q51426: TM-score 0.83, RMSD 3.35 Å
- 7X7Q chain M against the predicted model Q51426: TM-score 0.82, RMSD 3.38 Å
- 7X7Q chain P against the predicted model Q51426: TM-score 0.80, RMSD 3.63 Å
Elsewhere
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