UniProt Q4VY12
Phosphatase and actin regulator (Q4VY12)
Phosphatase and actin regulator (UniProt Q4VY12), EC 3.1.3.16: 12 experimental structures on GenesisL1, 2 ligands bound, 118 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q4VY12
- Protein
- Phosphatase and actin regulator
- EC
- 3.1.3.16
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 118 · 12 records with a druggable one
Structures
12 records of Q4VY12 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6ZEE | Structure of PP1(7-300) bound to Phactr1 (507-580) at pH8.4 | x-ray diffraction | W, X, D, C, U, V | SO4 | 18 (best 0.81) |
| 6ZEE | Structure of PP1(7-300) bound to PHACTR1 (507-580) at PH8.4 | x-ray diffraction | W, X, D, C, U, V | SO4 | 18 (best 0.81) |
| 6ZEF | Structure of PP1(7-300) bound to Phactr1 (516-580) at pH 5.25 | x-ray diffraction | C, D | — | 10 (best 0.64) |
| 6ZEF | Structure of PP1(7-300) bound to PHACTR1 (516-580) at pH 5.25 | x-ray diffraction | C, D | — | 10 (best 0.64) |
| 6ZEG | Structure of PP1-IRSp53 chimera [PP1(7-304) + linker (G/S)x9 + IRSp53(449-465)] bound to Phactr1… | x-ray diffraction | C, D | — | 3 (best 0.69) |
| 6ZEG | Structure of PP1-IRSP53 chimera [PP1(7-304) + linker (G/S)X9 + IRSP53(449-465)] bound to PHACTR1… | x-ray diffraction | C, D | — | 3 (best 0.69) |
| 6ZEH | Structure of PP1-spectrin alpha II chimera [PP1(7-304) + linker (G/S)x9 + spectrin alpha II… | x-ray diffraction | C, D | — | 3 (best 0.68) |
| 6ZEH | Structure of PP1-spectrin alpha II chimera [PP1(7-304) + linker (G/S) X9 + spectrin alpha II… | x-ray diffraction | C, D | — | 3 (best 0.68) |
| 6ZEI | Structure of PP1-IRSp53 S455E chimera [PP1(7-304) + linker (G/S)x9 + IRSp53(449-465)] bound to… | x-ray diffraction | C, D | — | 5 (best 0.68) |
| 6ZEI | Structure of PP1-IRSP53 S455E chimera [PP1(7-304) + linker (G/S)X9 + IRSP53(449-465)] bound to… | x-ray diffraction | C, D | — | 5 (best 0.68) |
| 6ZEJ | Structure of PP1-Phactr1 chimera [PP1(7-304) + linker (SGSGS) + Phactr1(526-580)] | x-ray diffraction | D, A, F, I, L, O | MN | 20 (best 0.77) |
| 6ZEJ | Structure of PP1-PHACTR1 chimera [PP1(7-304) + linker (sgsgs) + PHACTR1(526-580)] | x-ray diffraction | D, A, F, I, L, O | MN | 20 (best 0.77) |
Ligands
Experiment against prediction
- 6ZEJ chain O against the predicted model P62136: TM-score 0.86, RMSD 2.11 Å
- 6ZEJ chain I against the predicted model P62136: TM-score 0.86, RMSD 2.14 Å
- 6ZEJ chain I against the predicted model P62136: TM-score 0.86, RMSD 2.14 Å
- 6ZEJ chain L against the predicted model P62136: TM-score 0.86, RMSD 2.12 Å
- 6ZEJ chain A against the predicted model P62136: TM-score 0.86, RMSD 2.13 Å
- 6ZEJ chain A against the predicted model P62136: TM-score 0.86, RMSD 2.13 Å
- 6ZEJ chain D against the predicted model P62136: TM-score 0.86, RMSD 2.13 Å
- 6ZEJ chain D against the predicted model P62136: TM-score 0.86, RMSD 2.13 Å
- 6ZEJ chain F against the predicted model P62136: TM-score 0.86, RMSD 2.04 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.