UniProt Q4QAU9
fumarate hydratase (Q4QAU9)
fumarate hydratase (UniProt Q4QAU9), EC 4.2.1.2: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q4QAU9
- Protein
- fumarate hydratase
- EC
- 4.2.1.2
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 20 · 1 record with a druggable one
Structures
3 records of Q4QAU9 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6MSO | Crystal structure of mitochondrial fumarate hydratase from Leishmania major in a complex with… | x-ray diffraction | A, B, C, D | SF4, JYD | 20 (best 0.76) |
| 6MSO | Crystal structure of mitochondrial fumarate hydratase from leishmania major in a complex with… | x-ray diffraction | A, B, C, D | SF4, JYD | — |
| Q4QAU9 | AlphaFold monomer V2.0 prediction for fumarate hydratase 1, mitochondrial (Q4QAU9) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6MSO chain A against the predicted model Q4QAU9: TM-score 1.00, RMSD 0.56 Å
- 6MSO chain A against the predicted model Q4QAU9: TM-score 1.00, RMSD 0.56 Å
- 6MSO chain B against the predicted model Q4QAU9: TM-score 1.00, RMSD 0.57 Å
- 6MSO chain B against the predicted model Q4QAU9: TM-score 1.00, RMSD 0.57 Å
- 6MSO chain D against the predicted model Q4QAU9: TM-score 0.99, RMSD 0.60 Å
- 6MSO chain D against the predicted model Q4QAU9: TM-score 0.99, RMSD 0.60 Å
- 6MSO chain C against the predicted model Q4QAU9: TM-score 0.99, RMSD 0.62 Å
- 6MSO chain C against the predicted model Q4QAU9: TM-score 0.99, RMSD 0.62 Å
Elsewhere
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