UniProt Q4L5E4

Phenylalanyl-tRNA synthetase beta chain (Q4L5E4)

Phenylalanyl-tRNA synthetase beta chain (UniProt Q4L5E4), EC 6.1.1.20: 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 67 pockets. Binding sites, druggability and experiment against prediction…

UniProt: Q4L5E4
Protein: Phenylalanyl-tRNA synthetase beta chain
EC: 6.1.1.20
Experimental structures: 4
Predicted models: 1
Ligands: 1
Pockets: 67 · 5 records with a druggable one

Structures

5 records of Q4L5E4 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
2RHQ	PheRS from Staphylococcus haemolyticus- rational protein engineering and inhibitor studies	x-ray diffraction	B	—	11 (best 0.81)
2RHQ	Phers from staphylococcus haemolyticus- rational protein engineering and inhibitor studies	x-ray diffraction	B	—	11 (best 0.81)
2RHS	PheRS from Staphylococcus haemolyticus- rational protein engineering and inhibitor studies	x-ray diffraction	B, D	SO4	20 (best 0.85)
2RHS	Phers from staphylococcus haemolyticus- rational protein engineering and inhibitor studies	x-ray diffraction	B, D	SO4	20 (best 0.85)
Q4L5E4	AlphaFold monomer V2.0 prediction for phenylalanine--tRNA ligase beta subunit (Q4L5E4)	predicted	A	—	5 (best 0.64)

Ligands

SO4 · Sulfate ion · in 2 records

Experiment against prediction

2RHQ chain B against the predicted model Q4L5E4: TM-score 0.99, RMSD 0.87 Å
2RHQ chain B against the predicted model Q4L5E4: TM-score 0.99, RMSD 0.87 Å
2RHS chain D against the predicted model Q4L5E4: TM-score 0.97, RMSD 1.60 Å
2RHS chain D against the predicted model Q4L5E4: TM-score 0.97, RMSD 1.60 Å
2RHS chain B against the predicted model Q4L5E4: TM-score 0.94, RMSD 2.55 Å
2RHS chain B against the predicted model Q4L5E4: TM-score 0.94, RMSD 2.55 Å

Elsewhere

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