UniProt Q4FZW5

Nucleoporin SEH1-A (Q4FZW5)

Nucleoporin SEH1-A (UniProt Q4FZW5): 5 experimental structures and 1 predicted model on GenesisL1, 23 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q4FZW5
Protein: Nucleoporin SEH1-A
Experimental structures: 5
Predicted models: 1
Pockets: 23 · 5 records with a druggable one

Structures

6 records of Q4FZW5 in the MolNFT archive: 5 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6LK8	Structure of Xenopus laevis Cytoplasmic Ring subunit.	electron microscopy	D, d	—	1 (best 0.80)
6LK8	Structure of xenopus laevis cytoplasmic ring subunit.	electron microscopy	D, d	—	—
7TDZ	Cryo-EM model of protomer of the cytoplasmic ring of the nuclear pore complex from Xenopus laevis	electron microscopy	E, e	—	5 (best 0.84)
7VCI	Structure of Xenopus laevis NPC nuclear ring asymmetric unit	electron microscopy	C, L	—	4 (best 0.89)
7VOP	Cryo-EM structure of Xenopus laevis nuclear pore complex cytoplasmic ring subunit	electron microscopy	C, L	—	9 (best 0.89)
Q4FZW5	AlphaFold monomer V2.0 prediction for nucleoporin SEH1-a (Q4FZW5)	predicted	A	—	4 (best 0.74)

Experiment against prediction

7TDZ chain E against the predicted model Q4FZW5: TM-score 0.98, RMSD 1.27 Å
6LK8 chain d against the predicted model Q4FZW5: TM-score 0.96, RMSD 1.46 Å
6LK8 chain d against the predicted model Q4FZW5: TM-score 0.96, RMSD 1.46 Å
6LK8 chain D against the predicted model Q4FZW5: TM-score 0.94, RMSD 1.92 Å
6LK8 chain D against the predicted model Q4FZW5: TM-score 0.94, RMSD 1.92 Å
7VCI chain L against the predicted model Q4FZW5: TM-score 0.91, RMSD 2.42 Å
7VCI chain C against the predicted model Q4FZW5: TM-score 0.90, RMSD 2.41 Å
7VOP chain C against the predicted model Q4FZW5: TM-score 0.87, RMSD 2.69 Å
7VOP chain L against the predicted model Q4FZW5: TM-score 0.85, RMSD 2.90 Å

Elsewhere

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