UniProt Q4DJ07
Prostaglandin F synthase (Q4DJ07)
Prostaglandin F synthase (UniProt Q4DJ07), EC 1.1.1.188: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 19 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q4DJ07
- Protein
- Prostaglandin F synthase
- EC
- 1.1.1.188
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 19 · 5 records with a druggable one
Structures
5 records of Q4DJ07 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4FZI | Crystal structure of prostaglandin F synthase from Trypanosoma cruzi | x-ray diffraction | A, B | GLU, SO4 | 6 (best 0.63) |
| 4FZI | Crystal structure of prostaglandin F synthase from trypanosoma cruzi | x-ray diffraction | A, B | GLU, SO4 | 6 (best 0.63) |
| 4GIE | Crystal structure of prostaglandin F synthase from Trypanosoma cruzi bound to NADP | x-ray diffraction | A | NAP | 2 (best 0.64) |
| 4GIE | Crystal structure of prostaglandin F synthase from trypanosoma cruzi bound to NADP | x-ray diffraction | A | NAP | 2 (best 0.64) |
| Q4DJ07 | AlphaFold monomer V2.0 prediction for 9,11-endoperoxide prostaglandin H2 reductase (Q4DJ07) | predicted | A | — | 3 (best 0.63) |
Ligands
Experiment against prediction
- 4FZI chain B against the predicted model Q4DJ07: TM-score 1.00, RMSD 0.33 Å
- 4FZI chain B against the predicted model Q4DJ07: TM-score 1.00, RMSD 0.33 Å
- 4GIE chain A against the predicted model Q4DJ07: TM-score 0.97, RMSD 0.25 Å
- 4GIE chain A against the predicted model Q4DJ07: TM-score 0.97, RMSD 0.25 Å
- 4FZI chain A against the predicted model Q4DJ07: TM-score 0.98, RMSD 0.97 Å
- 4FZI chain A against the predicted model Q4DJ07: TM-score 0.98, RMSD 0.97 Å
Elsewhere
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