UniProt Q496J9
Synaptic vesicle glycoprotein 2C (Q496J9)
Synaptic vesicle glycoprotein 2C (UniProt Q496J9): 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q496J9
- Protein
- Synaptic vesicle glycoprotein 2C
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 16 · 1 record with a druggable one
Structures
9 records of Q496J9 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4JRA | CRYSTAL STRUCTURE OF THE BOTULINUM NEUROTOXIN A RECEPTOR-BINDING DOMAIN IN COMPLEX WITH THE LUMINAL… | x-ray diffraction | C, D | — | 2 (best 0.43) |
| 4JRA | Crystal structure of the botulinum neurotoxin a receptor-binding domain in complex with the luminal… | x-ray diffraction | C, D | — | — |
| 5JLV | Receptor binding domain of Botulinum neurotoxin A in complex with human glycosylated SV2C | x-ray diffraction | C, D | NAG, FUC | 6 (best 0.46) |
| 5JLV | Receptor binding domain of botulinum neurotoxin a in complex with human glycosylated SV2C | x-ray diffraction | C, D | — | — |
| 5MOY | Crystal structure of the BoNT/A2 receptor-binding domain in complex with the luminal domain of its… | x-ray diffraction | B | — | 2 (best 0.40) |
| 5MOY | Crystal structure of the BONT/A2 receptor-binding domain in complex with the luminal domain of its… | x-ray diffraction | B | — | — |
| 6ES1 | Crystal structure of the binding domain from botulinum neurotoxin A2 bound to extracellular domain… | x-ray diffraction | B | — | 2 (best 0.48) |
| 6ES1 | Crystal structure of the binding domain from botulinum neurotoxin A2 bound to extracellular domain… | x-ray diffraction | B | — | — |
| Q496J9 | AlphaFold monomer V2.0 prediction for synaptic vesicle glycoprotein 2C (Q496J9) | predicted | A | — | 4 (best 0.77) |
Ligands
Experiment against prediction
- 4JRA chain C against the predicted model Q496J9: TM-score 0.97, RMSD 0.54 Å
- 4JRA chain C against the predicted model Q496J9: TM-score 0.97, RMSD 0.54 Å
- 5JLV chain D against the predicted model Q496J9: TM-score 0.97, RMSD 1.02 Å
- 5JLV chain D against the predicted model Q496J9: TM-score 0.97, RMSD 1.02 Å
- 6ES1 chain B against the predicted model Q496J9: TM-score 0.95, RMSD 0.89 Å
- 6ES1 chain B against the predicted model Q496J9: TM-score 0.95, RMSD 0.89 Å
- 4JRA chain D against the predicted model Q496J9: TM-score 0.95, RMSD 0.97 Å
- 4JRA chain D against the predicted model Q496J9: TM-score 0.95, RMSD 0.97 Å
- 5JLV chain C against the predicted model Q496J9: TM-score 0.91, RMSD 1.28 Å
- 5JLV chain C against the predicted model Q496J9: TM-score 0.91, RMSD 1.28 Å
Elsewhere
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