UniProt Q46897
CRISPR system Cascade subunit CasE (Q46897)
CRISPR system Cascade subunit CasE (UniProt Q46897), EC 3.1.-.-: 12 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q46897
- Protein
- CRISPR system Cascade subunit CasE
- EC
- 3.1.-.-
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
13 records of Q46897 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4DZD | Crystal structure of the CRISPR-associated protein Cas6e from Escherichia coli str. K-12 | x-ray diffraction | A | — | — |
| 4DZD | Crystal structure of the CRISPR-associated protein CAS6E from escherichia COLI str. K-12 | x-ray diffraction | A | — | — |
| 4QYZ | Crystal structure of a CRISPR RNA-guided surveillance complex, Cascade, bound to a ssDNA target | x-ray diffraction | K | — | — |
| 4QYZ | Crystal structure of a CRISPR RNA-guided surveillance complex, cascade, bound to a ssdna target | x-ray diffraction | K | — | — |
| 4TVX | Crystal structure of the E. coli CRISPR RNA-guided surveillance complex, Cascade | x-ray diffraction | A, M | — | — |
| 4U7U | Crystal structure of RNA-guided immune Cascade complex from E.coli | x-ray diffraction | D, P | — | — |
| 4U7U | Crystal structure of RNA-guided immune cascade complex from E.COLI | x-ray diffraction | D, P | — | — |
| 5CD4 | The Type IE CRISPR Cascade complex from E. coli, with two assemblies in the asymmetric unit… | x-ray diffraction | A, M | — | 5 (best 0.81) |
| 5CD4 | The type ie CRISPR cascade complex from E. COLI, with two assemblies in the asymmetric unit… | x-ray diffraction | A, M | — | — |
| 5H9E | Crystal structure of E. COLI cascade bound to a pam-containing dsdna target (32-nt spacer) at 3.20… | x-ray diffraction | K | — | — |
| 5H9F | Crystal structure of E. coli Cascade bound to a PAM-containing dsDNA target at 2.45 angstrom… | x-ray diffraction | K | — | — |
| 5H9F | Crystal structure of E. COLI cascade bound to a pam-containing dsdna target at 2.45 ångström… | x-ray diffraction | K | — | — |
| Q46897 | AlphaFold monomer V2.0 prediction for CRISPR system cascade subunit case (Q46897) | predicted | A | — | — |
Experiment against prediction
- 5H9F chain K against the predicted model Q46897: TM-score 0.98, RMSD 0.69 Å
- 5H9F chain K against the predicted model Q46897: TM-score 0.98, RMSD 0.69 Å
- 4TVX chain M against the predicted model Q46897: TM-score 0.97, RMSD 0.92 Å
- 5CD4 chain M against the predicted model Q46897: TM-score 0.97, RMSD 0.91 Å
- 5CD4 chain M against the predicted model Q46897: TM-score 0.97, RMSD 0.91 Å
- 5H9E chain K against the predicted model Q46897: TM-score 0.97, RMSD 0.77 Å
- 4TVX chain A against the predicted model Q46897: TM-score 0.97, RMSD 0.97 Å
- 5CD4 chain A against the predicted model Q46897: TM-score 0.97, RMSD 1.04 Å
- 5CD4 chain A against the predicted model Q46897: TM-score 0.97, RMSD 1.04 Å
- 4U7U chain D against the predicted model Q46897: TM-score 0.97, RMSD 0.81 Å
Elsewhere
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