UniProt Q45618
Putative transposase for insertion sequence element IS5376 (Q45618)
Putative transposase for insertion sequence element IS5376 (UniProt Q45618): 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 29 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q45618
- Protein
- Putative transposase for insertion sequence element IS5376
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 29 · 3 records with a druggable one
Structures
3 records of Q45618 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8B4H | IstA transposase cleaved donor complex | electron microscopy | A, B, C, D | MG | 20 (best 0.76) |
| 8Q4D | IstA-IstB(E167Q) Strand Transfer Complex | electron microscopy | A, B, C, D | MG, ADP | 6 (best 0.81) |
| Q45618 | AlphaFold monomer V2.0 prediction for putative transposase for insertion sequence element IS5376… | predicted | A | — | 3 (best 0.52) |
Ligands
Experiment against prediction
- 8Q4D chain A against the predicted model Q45618: TM-score 0.66, RMSD 1.80 Å
- 8Q4D chain B against the predicted model Q45618: TM-score 0.66, RMSD 1.80 Å
- 8B4H chain A against the predicted model Q45618: TM-score 0.63, RMSD 3.37 Å
- 8B4H chain B against the predicted model Q45618: TM-score 0.63, RMSD 3.37 Å
- 8Q4D chain C against the predicted model Q45618: TM-score 0.63, RMSD 2.81 Å
- 8Q4D chain D against the predicted model Q45618: TM-score 0.63, RMSD 2.81 Å
- 8B4H chain C against the predicted model Q45618: TM-score 0.62, RMSD 2.64 Å
- 8B4H chain D against the predicted model Q45618: TM-score 0.62, RMSD 2.64 Å
Elsewhere
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