UniProt Q44238
OPAA organophosphate prolidase anhydrolase (Q44238)
OPAA organophosphate prolidase anhydrolase (UniProt Q44238), EC 3.4.13.9: 10 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 19 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q44238
- Protein
- OPAA organophosphate prolidase anhydrolase
- EC
- 3.4.13.9
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 19 · 3 records with a druggable one
Structures
11 records of Q44238 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3L24 | Crystal Structure of the Nerve Agent Degrading Organophosphate Anhydrolase/Prolidase in Complex… | x-ray diffraction | A, B, C | — | — |
| 3L24 | Crystal structure of the nerve agent degrading organophosphate ANHYDROLASE/PROLIDASE in complex… | x-ray diffraction | A, B, C | — | — |
| 3L7G | Crystal structure of organophosphate anhydrolase/prolidase | x-ray diffraction | A, B, C | — | — |
| 3L7G | Crystal structure of organophosphate ANHYDROLASE/PROLIDASE | x-ray diffraction | A, B, C | — | — |
| 4ZWO | Crystal structure of organophosphate anhydrolase/prolidase mutant Y212F | x-ray diffraction | A, B | MN, GOA | 7 (best 0.85) |
| 4ZWO | Crystal structure of organophosphate ANHYDROLASE/PROLIDASE mutant Y212F | x-ray diffraction | A, B | — | — |
| 4ZWP | Crystal structure of organophosphate anhydrolase/prolidase mutant Y212F | x-ray diffraction | A, B | MN, BA, M44 | 7 (best 0.85) |
| 4ZWP | Crystal structure of organophosphate ANHYDROLASE/PROLIDASE mutant Y212F | x-ray diffraction | A, B | — | — |
| 4ZWU | Crystal structure of organophosphate anhydrolase/prolidase mutant Y212F, V342L, I215Y | x-ray diffraction | A, B | — | — |
| 4ZWU | Crystal structure of organophosphate ANHYDROLASE/PROLIDASE mutant Y212F, V342L, I215Y | x-ray diffraction | A, B | — | — |
| Q44238 | AlphaFold monomer V2.0 prediction for xaa-pro dipeptidase (Q44238) | predicted | A | — | 5 (best 0.59) |
Ligands
Experiment against prediction
- 4ZWO chain A against the predicted model Q44238: TM-score 1.00, RMSD 0.48 Å
- 4ZWO chain A against the predicted model Q44238: TM-score 1.00, RMSD 0.48 Å
- 4ZWP chain A against the predicted model Q44238: TM-score 1.00, RMSD 0.49 Å
- 4ZWP chain A against the predicted model Q44238: TM-score 1.00, RMSD 0.49 Å
- 4ZWU chain A against the predicted model Q44238: TM-score 1.00, RMSD 0.51 Å
- 4ZWU chain A against the predicted model Q44238: TM-score 1.00, RMSD 0.51 Å
- 4ZWP chain B against the predicted model Q44238: TM-score 1.00, RMSD 0.63 Å
- 4ZWP chain B against the predicted model Q44238: TM-score 1.00, RMSD 0.63 Å
- 4ZWO chain B against the predicted model Q44238: TM-score 1.00, RMSD 0.57 Å
- 4ZWO chain B against the predicted model Q44238: TM-score 1.00, RMSD 0.57 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.