UniProt Q401N2
Ligand-gated cation channel ZACN (Q401N2)
Ligand-gated cation channel ZACN (UniProt Q401N2): 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 65 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q401N2
- Protein
- Ligand-gated cation channel ZACN
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 65 · 3 records with a druggable one
Structures
4 records of Q401N2 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8YX6 | Structure of a Cys-loop Receptor in Zinc Binding State | electron microscopy | A, B, C, D, E | NAG, ZN | 20 (best 0.84) |
| 8YX7 | Structure of a Cys-loop Receptor under Acidic Condition | electron microscopy | A, B, C, D, E | NAG | 20 (best 0.85) |
| 8YX8 | Structure of a Cys-loop Receptor in Apo State | electron microscopy | A, B, C, D, E | NAG | 20 (best 0.84) |
| Q401N2 | AlphaFold monomer V2.0 prediction for zinc-activated ligand-gated ion channel (Q401N2) | predicted | A | — | 5 (best 0.48) |
Ligands
Experiment against prediction
- 8YX6 chain A against the predicted model Q401N2: TM-score 0.96, RMSD 1.41 Å
- 8YX8 chain A against the predicted model Q401N2: TM-score 0.96, RMSD 1.42 Å
- 8YX7 chain A against the predicted model Q401N2: TM-score 0.96, RMSD 1.42 Å
Elsewhere
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