UniProt Q3ZT31
Sorting nexin-25 (Q3ZT31)
Sorting nexin-25 (UniProt Q3ZT31): 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q3ZT31
- Protein
- Sorting nexin-25
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 15 · 2 records with a druggable one
Structures
4 records of Q3ZT31 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7WF8 | Crystal structure of mouse SNX25 RGS domain in space group P212121 | x-ray diffraction | A, B | CL | 2 (best 0.31) |
| 7WF9 | Crystal structure of mouse SNX25 RGS domain in space group P41212 | x-ray diffraction | A, B | — | 1 (best 0.34) |
| 8HQL | Crystal structure of mouse SNX25 PX domain | x-ray diffraction | A, B, C, D, E | CL | 1 (best 0.59) |
| Q3ZT31 | AlphaFold monomer V2.0 prediction for sorting nexin-25 (Q3ZT31) | predicted | A | — | 11 (best 0.75) |
Ligands
- CL · Chloride ion · in 2 records
Experiment against prediction
- 7WF8 chain A against the predicted model Q3ZT31: TM-score 0.95, RMSD 1.20 Å
- 7WF8 chain B against the predicted model Q3ZT31: TM-score 0.95, RMSD 1.05 Å
- 8HQL chain D against the predicted model Q3ZT31: TM-score 0.88, RMSD 1.97 Å
- 8HQL chain E against the predicted model Q3ZT31: TM-score 0.88, RMSD 2.09 Å
- 8HQL chain B against the predicted model Q3ZT31: TM-score 0.88, RMSD 2.15 Å
- 8HQL chain A against the predicted model Q3ZT31: TM-score 0.87, RMSD 2.18 Å
- 7WF9 chain B against the predicted model Q3ZT31: TM-score 0.58, RMSD 1.95 Å
- 7WF9 chain A against the predicted model Q3ZT31: TM-score 0.57, RMSD 1.99 Å
Elsewhere
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