UniProt Q3UPF5
Zinc finger CCCH-type antiviral protein 1 (Q3UPF5)
Zinc finger CCCH-type antiviral protein 1 (UniProt Q3UPF5): 4 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q3UPF5
- Protein
- Zinc finger CCCH-type antiviral protein 1
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 26 · 4 records with a druggable one
Structures
5 records of Q3UPF5 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6L1W | Zinc-finger Antiviral Protein (ZAP) bound to RNA | x-ray diffraction | A | ZN | 4 (best 0.59) |
| 6L1W | Zinc-finger antiviral protein (zap) bound to RNA | x-ray diffraction | A | ZN | — |
| 7SZ2 | Mouse PARP13/ZAP ZnF5-WWE1-WWE2 bound to ATP | x-ray diffraction | A, B | ATP, PO4 | 6 (best 0.75) |
| 7SZ3 | Mouse PARP13/ZAP ZnF5-WWE1-WWE2 bound to ADPr | x-ray diffraction | A, B | APR, PO4 | 5 (best 0.76) |
| Q3UPF5 | AlphaFold monomer V2.0 prediction for zinc finger ccch-type antiviral protein 1 (Q3UPF5) | predicted | A | — | 11 (best 0.69) |
Ligands
Experiment against prediction
- 6L1W chain A against the predicted model Q3UPF5: TM-score 0.94, RMSD 1.38 Å
- 6L1W chain A against the predicted model Q3UPF5: TM-score 0.94, RMSD 1.38 Å
- 7SZ3 chain B against the predicted model Q3UPF5: TM-score 0.58, RMSD 3.75 Å
- 7SZ2 chain B against the predicted model Q3UPF5: TM-score 0.58, RMSD 3.73 Å
- 7SZ2 chain A against the predicted model Q3UPF5: TM-score 0.58, RMSD 3.67 Å
- 7SZ3 chain A against the predicted model Q3UPF5: TM-score 0.57, RMSD 3.68 Å
Elsewhere
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