UniProt Q3UDT3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Q3UDT3)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (UniProt Q3UDT3), EC 2.7.1.153: 40 experimental structures on GenesisL1, 6 ligands bound, 75 pockets. Binding sites, pockets, druggability and 3D…
- UniProt
- Q3UDT3
- Protein
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
- EC
- 2.7.1.153
- Experimental structures
- 40
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 75 · 5 records with a druggable one
Structures
40 records of Q3UDT3 in the MolNFT archive: 40 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2WXF | The crystal structure of the murine class IA PI 3-kinase p110delta in complex with PIK-39. | x-ray diffraction | A | — | — |
| 2WXF | The crystal structure of the murine class ia pi 3-kinase P110DELTA in complex with pik-39. | x-ray diffraction | A | — | — |
| 2WXG | The crystal structure of the murine class IA PI 3-kinase p110delta in complex with SW13. | x-ray diffraction | A | — | — |
| 2WXG | The crystal structure of the murine class ia pi 3-kinase P110DELTA in complex with SW13. | x-ray diffraction | A | — | — |
| 2WXH | The crystal structure of the murine class IA PI 3-kinase p110delta in complex with SW14. | x-ray diffraction | A | — | — |
| 2WXH | The crystal structure of the murine class ia pi 3-kinase P110DELTA in complex with SW14. | x-ray diffraction | A | — | — |
| 2WXI | The crystal structure of the murine class IA PI 3-kinase p110delta in complex with SW30. | x-ray diffraction | A | — | — |
| 2WXI | The crystal structure of the murine class ia pi 3-kinase P110DELTA in complex with SW30. | x-ray diffraction | A | — | — |
| 2WXJ | The crystal structure of the murine class IA PI 3-kinase p110delta in complex with INK654. | x-ray diffraction | A | — | — |
| 2WXJ | The crystal structure of the murine class ia pi 3-kinase P110DELTA in complex with INK654. | x-ray diffraction | A | — | — |
| 2WXK | The crystal structure of the murine class IA PI 3-kinase p110delta in complex with INK666. | x-ray diffraction | A | — | — |
| 2WXK | The crystal structure of the murine class ia pi 3-kinase P110DELTA in complex with INK666. | x-ray diffraction | A | — | — |
| 2WXL | The crystal structure of the murine class IA PI 3-kinase p110delta in complex with ZSTK474. | x-ray diffraction | A | — | — |
| 2WXL | The crystal structure of the murine class ia pi 3-kinase P110DELTA in complex with ZSTK474. | x-ray diffraction | A | — | — |
| 2WXM | The crystal structure of the murine class IA PI 3-kinase p110delta in complex with DL06. | x-ray diffraction | A | — | — |
| 2WXM | The crystal structure of the murine class ia pi 3-kinase P110DELTA in complex with DL06. | x-ray diffraction | A | — | — |
| 2WXN | The crystal structure of the murine class IA PI 3-kinase p110delta in complex with DL07. | x-ray diffraction | A | — | — |
| 2WXN | The crystal structure of the murine class ia pi 3-kinase P110DELTA in complex with DL07. | x-ray diffraction | A | — | — |
| 2WXO | The crystal structure of the murine class IA PI 3-kinase p110delta in complex with AS5. | x-ray diffraction | A | — | — |
| 2WXO | The crystal structure of the murine class ia pi 3-kinase P110DELTA in complex with AS5. | x-ray diffraction | A | — | — |
| 2WXP | The crystal structure of the murine class IA PI 3-kinase p110delta in complex with GDC-0941. | x-ray diffraction | A | — | — |
| 2WXP | The crystal structure of the murine class ia pi 3-kinase P110DELTA in complex with gdc-0941. | x-ray diffraction | A | — | — |
| 2WXQ | The crystal structure of the murine class IA PI 3-kinase p110delta in complex with AS15. | x-ray diffraction | A | — | — |
| 2WXQ | The crystal structure of the murine class ia pi 3-kinase P110DELTA in complex with AS15. | x-ray diffraction | A | — | — |
| 2WXR | The crystal structure of the murine class IA PI 3-kinase p110delta. | x-ray diffraction | A | — | — |
| 2WXR | The crystal structure of the murine class ia pi 3-kinase P110DELTA. | x-ray diffraction | A | — | — |
| 2X38 | The crystal structure of the murine class IA PI 3-kinase p110delta in complex with IC87114. | x-ray diffraction | A | — | — |
| 2X38 | The crystal structure of the murine class ia pi 3-kinase P110DELTA in complex with IC87114. | x-ray diffraction | A | — | — |
| 5IS5 | Discovery and Pharmacological Characterization of Novel Quinazoline-based PI3K delta-selective… | x-ray diffraction | A | 6CY | — |
| 5IS5 | Discovery and pharmacological characterization of novel quinazoline- based PI3K delta-selective… | x-ray diffraction | A | — | — |
| 5NGB | X-Ray Diffraction Crystal Structure of the murine PI3K p110delta in complex with a pan inhibitor | x-ray diffraction | A | 8WH | 12 (best 0.81) |
| 5NGB | X-ray diffraction crystal structure of the murine PI3K P110DELTA in complex with a pan inhibitor | x-ray diffraction | A | 8WH | — |
| 6EYZ | PI3 kinase delta in complex with 4-Fluorophenyl 5-(4-(5-((4-isopropylpiperazin-1-yl)methyl)oxazol-2… | x-ray diffraction | A | C5W | 11 (best 0.81) |
| 6EYZ | PI3 kinase delta in complex with 4-fluorophenyl 5-(4-(5-((4… | x-ray diffraction | A | C5W | — |
| 6HI9 | PI3 Kinase Delta in complex with 3[6(oxan4yl)pyridin2yl]phenol | x-ray diffraction | A | G68 | 12 (best 0.81) |
| 6HI9 | PI3 kinase delta in complex with 3[6(OXAN4YL)PYRIDIN2YL]PHENOL | x-ray diffraction | A | G68 | — |
| 6MUL | Murine PI3K delta kinsae domain - cpd 1 | x-ray diffraction | A, B | K4A | 20 (best 0.82) |
| 6MUL | Murine PI3K delta kinsae domain - cpd 1 | x-ray diffraction | A, B | K4A | — |
| 6MUM | Murine PI3K delta kinsae domain - cpd 3 | x-ray diffraction | A, B | K47 | 20 (best 0.81) |
| 6MUM | Murine PI3K delta kinsae domain - cpd 3 | x-ray diffraction | A, B | K47 | — |
Ligands
- 8WH · 3-[[4-(2-morpholin-4-yl-4-oxidanylidene-3~{H}-quinolin-8-yl)-1,2,3-triazol-1-yl]methyl]benzoic acid · in 2 records
- C5W · 2-methoxy-5-[4-[5-[(4-propan-2-ylpiperazin-1-yl) methyl]-1,3-oxazol-2-yl]-2~{H}-indazol-6-yl]pyridine-3-carboxylic acid · in 2 records
- G68 · 3-[6-(oxan-4-yl)pyridin-2-yl]phenol · in 2 records
- K47 · [(3S)-3-{[8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-9H-purin-6-yl]oxy}pyrrolidin-1-yl](oxan-4-yl) methanone · in 2 records
- K4A · 1-{1-[8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-9H-purin-6-yl]piperidin-4-yl}-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one · in 2 records
- 6CY · 5-{4-[3-(4-acetylpiperazine-1-carbonyl)phenyl]quinazolin-6-yl}-2-methoxypyridine-3-carbonitrile · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.