UniProt Q3U5C8
Rho guanine nucleotide exchange factor 16 (Q3U5C8)
Rho guanine nucleotide exchange factor 16 (UniProt Q3U5C8): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 60 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q3U5C8
- Protein
- Rho guanine nucleotide exchange factor 16
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 60 · 4 records with a druggable one
Structures
7 records of Q3U5C8 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7CSO | Structure of Ephexin4 DH-PH-SH3 | x-ray diffraction | A, B, C, D | SO4 | 18 (best 0.79) |
| 7CSO | Structure of EPHEXIN4 dh-pH-SH3 | x-ray diffraction | A, B, C, D | SO4 | — |
| 7CSP | Structure of Ephexin4 IDPSH | x-ray diffraction | A, B | — | 14 (best 0.78) |
| 7CSP | Structure of EPHEXIN4 idpsh | x-ray diffraction | A, B | — | — |
| 7CSR | Structure of Ephexin4 R676L | x-ray diffraction | A, B, C | — | 14 (best 0.78) |
| 7CSR | Structure of EPHEXIN4 R676L | x-ray diffraction | A, B, C | — | 14 (best 0.78) |
| Q3U5C8 | AlphaFold monomer V2.0 prediction for rho guanine nucleotide exchange factor 16 (Q3U5C8) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 7CSP chain B against the predicted model Q3U5C8: TM-score 0.69, RMSD 5.25 Å
- 7CSP chain B against the predicted model Q3U5C8: TM-score 0.69, RMSD 5.25 Å
- 7CSO chain C against the predicted model Q3U5C8: TM-score 0.68, RMSD 5.28 Å
- 7CSO chain C against the predicted model Q3U5C8: TM-score 0.68, RMSD 5.28 Å
- 7CSR chain B against the predicted model Q3U5C8: TM-score 0.68, RMSD 5.41 Å
- 7CSR chain B against the predicted model Q3U5C8: TM-score 0.68, RMSD 5.41 Å
- 7CSO chain D against the predicted model Q3U5C8: TM-score 0.68, RMSD 5.36 Å
- 7CSO chain D against the predicted model Q3U5C8: TM-score 0.68, RMSD 5.36 Å
- 7CSR chain C against the predicted model Q3U5C8: TM-score 0.67, RMSD 5.48 Å
- 7CSR chain C against the predicted model Q3U5C8: TM-score 0.67, RMSD 5.48 Å
Elsewhere
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