UniProt Q3U182
CREB-regulated transcription coactivator 2 (Q3U182)
CREB-regulated transcription coactivator 2 (UniProt Q3U182): 4 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q3U182
- Protein
- CREB-regulated transcription coactivator 2
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
5 records of Q3U182 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5ZK1 | Crystal Structure of the CRTC2(SeMet)-CREB-CRE complex | x-ray diffraction | C | — | — |
| 5ZK1 | Crystal structure of the CRTC2(SEMET)-creb-cre complex | x-ray diffraction | C | — | — |
| 5ZKO | Crystal structure of the CRTC2-CREB-CRE complex | x-ray diffraction | G, H | — | 6 (best 0.78) |
| 5ZKO | Crystal structure of the CRTC2-creb-cre complex | x-ray diffraction | G, H | — | — |
| Q3U182 | AlphaFold monomer V2.0 prediction for creb-regulated transcription coactivator 2 (Q3U182) | predicted | A | — | — |
Experiment against prediction
- 5ZKO chain G against the predicted model Q3U182: TM-score 0.94, RMSD 0.52 Å
- 5ZKO chain G against the predicted model Q3U182: TM-score 0.94, RMSD 0.52 Å
- 5ZKO chain H against the predicted model Q3U182: TM-score 0.91, RMSD 0.70 Å
- 5ZKO chain H against the predicted model Q3U182: TM-score 0.91, RMSD 0.70 Å
- 5ZK1 chain C against the predicted model Q3U182: TM-score 0.85, RMSD 0.84 Å
- 5ZK1 chain C against the predicted model Q3U182: TM-score 0.85, RMSD 0.84 Å
Elsewhere
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