UniProt Q3SZI4

14-3-3 protein theta (Q3SZI4)

14-3-3 protein theta (UniProt Q3SZI4): 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q3SZI4
Protein: 14-3-3 protein theta
Experimental structures: 4
Predicted models: 1
Ligands: 1
Pockets: 12 · 1 record with a druggable one

Structures

5 records of Q3SZI4 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6BCY	Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at T360	x-ray diffraction	A, B, E, F	MG	12 (best 0.80)
6BCY	Complex of 14-3-3 theta with an IRSP53 peptide phosphorylated at T360	x-ray diffraction	A, B, E, F	MG	—
6BD1	Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at S366	x-ray diffraction	A, B, E, F	MG	—
6BD1	Complex of 14-3-3 theta with an IRSP53 peptide phosphorylated at S366	x-ray diffraction	A, B, E, F	MG	—
Q3SZI4	AlphaFold monomer V2.0 prediction for 14-3-3 protein theta (Q3SZI4)	predicted	A	—	—

Ligands

MG · Magnesium ion · in 4 records

Experiment against prediction

6BCY chain A against the predicted model Q3SZI4: TM-score 0.98, RMSD 0.92 Å
6BCY chain A against the predicted model Q3SZI4: TM-score 0.98, RMSD 0.92 Å
6BD1 chain B against the predicted model Q3SZI4: TM-score 0.98, RMSD 0.96 Å
6BD1 chain B against the predicted model Q3SZI4: TM-score 0.98, RMSD 0.96 Å
6BD1 chain F against the predicted model Q3SZI4: TM-score 0.98, RMSD 0.96 Å
6BD1 chain F against the predicted model Q3SZI4: TM-score 0.98, RMSD 0.96 Å
6BCY chain E against the predicted model Q3SZI4: TM-score 0.98, RMSD 0.99 Å
6BCY chain E against the predicted model Q3SZI4: TM-score 0.98, RMSD 0.99 Å
6BD1 chain E against the predicted model Q3SZI4: TM-score 0.98, RMSD 0.98 Å
6BD1 chain E against the predicted model Q3SZI4: TM-score 0.98, RMSD 0.98 Å

Elsewhere

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