UniProt Q3HWC9

NL4-3 protease (Q3HWC9)

NL4-3 protease (UniProt Q3HWC9): 4 experimental structures on GenesisL1, 2 ligands bound, 3 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt: Q3HWC9
Protein: NL4-3 protease
Experimental structures: 4
Predicted models: 0
Ligands: 2
Pockets: 3 · 2 records with a druggable one

Structures

4 records of Q3HWC9 in the MolNFT archive: 4 experimental, 0 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6OOS	HIV-1 Protease NL4-3 L90M Mutant in complex with darunavir	x-ray diffraction	B, D, A, C	SO4, 017	2 (best 0.74)
6OOS	HIV-1 protease NL4-3 L90M mutant in complex with darunavir	x-ray diffraction	B, D, A, C	SO4, 017	—
6OOT	HIV-1 Protease NL4-3 L89V, L90M Mutant in complex with darunavir	x-ray diffraction	A, B	SO4, 017	1 (best 0.68)
6OOT	HIV-1 protease NL4-3 L89V, L90M mutant in complex with darunavir	x-ray diffraction	A, B	SO4, 017	—

Ligands

017 · (3r,3as,6ar)-hexahydrofuro[2,3-b]furan-3-yl(1s,2r)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate · in 4 records
SO4 · Sulfate ion · in 4 records

Elsewhere

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