UniProt Q381M1
RNA uridylyl transferase (Q381M1)
RNA uridylyl transferase (UniProt Q381M1), EC 2.7.7.52: 14 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q381M1
- Protein
- RNA uridylyl transferase
- EC
- 2.7.7.52
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 16 · 3 records with a druggable one
Structures
15 records of Q381M1 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2IKF | Terminal uridylyl transferase 4 from Trypanosoma brucei with bound UTP | x-ray diffraction | A, B | MG, UTP | 8 (best 0.76) |
| 2IKF | Terminal uridylyl transferase 4 from trypanosoma brucei with bound UTP | x-ray diffraction | A, B | — | — |
| 2NOM | Terminal uridylyl transferase 4 from Trypanosoma brucei with bound dUTP | x-ray diffraction | A, B | MG, DUT | 6 (best 0.78) |
| 2NOM | Terminal uridylyl transferase 4 from trypanosoma brucei with bound dutp | x-ray diffraction | A, B | — | — |
| 2Q0C | Terminal uridylyl transferase 4 from Trypanosoma brucei with bound CTP | x-ray diffraction | A, B | — | — |
| 2Q0C | Terminal uridylyl transferase 4 from trypanosoma brucei with bound CTP | x-ray diffraction | A, B | — | — |
| 2Q0D | Terminal uridylyl transferase 4 from Trypanosoma brucei with bound ATP | x-ray diffraction | A, B | — | — |
| 2Q0D | Terminal uridylyl transferase 4 from trypanosoma brucei with bound ATP | x-ray diffraction | A, B | — | — |
| 2Q0E | Terminal uridylyl transferase 4 from Trypanosoma brucei with bound GTP | x-ray diffraction | A, B | — | — |
| 2Q0E | Terminal uridylyl transferase 4 from trypanosoma brucei with bound GTP | x-ray diffraction | A, B | — | — |
| 2Q0F | Terminal uridylyl transferase 4 from Trypanosoma brucei with bound UTP and UMP | x-ray diffraction | A, B | — | — |
| 2Q0F | Terminal uridylyl transferase 4 from trypanosoma brucei with bound UTP and ump | x-ray diffraction | A, B | — | — |
| 2Q0G | Terminal uridylyl transferase 4 from Trypanosoma brucei with bound UPU | x-ray diffraction | A, B | — | — |
| 2Q0G | Terminal uridylyl transferase 4 from trypanosoma brucei with bound upu | x-ray diffraction | A, B | — | — |
| Q381M1 | AlphaFold monomer V2.0 prediction for terminal uridylyltransferase 4 (Q381M1) | predicted | A | — | 2 (best 0.75) |
Ligands
Experiment against prediction
- 2NOM chain B against the predicted model Q381M1: TM-score 0.98, RMSD 1.00 Å
- 2NOM chain B against the predicted model Q381M1: TM-score 0.98, RMSD 1.00 Å
- 2Q0G chain B against the predicted model Q381M1: TM-score 0.97, RMSD 1.24 Å
- 2Q0G chain B against the predicted model Q381M1: TM-score 0.97, RMSD 1.24 Å
- 2IKF chain B against the predicted model Q381M1: TM-score 0.97, RMSD 1.27 Å
- 2IKF chain B against the predicted model Q381M1: TM-score 0.97, RMSD 1.27 Å
- 2Q0D chain B against the predicted model Q381M1: TM-score 0.97, RMSD 1.33 Å
- 2Q0D chain B against the predicted model Q381M1: TM-score 0.97, RMSD 1.33 Å
- 2Q0E chain B against the predicted model Q381M1: TM-score 0.96, RMSD 1.35 Å
- 2Q0E chain B against the predicted model Q381M1: TM-score 0.96, RMSD 1.35 Å
Elsewhere
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