UniProt Q33DX5
16S rRNA (guanine(1405)-N(7))-methyltransferase (Q33DX5)
16S rRNA (guanine(1405)-N(7))-methyltransferase (UniProt Q33DX5), EC 2.1.1.179: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 28 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q33DX5
- Protein
- 16S rRNA (guanine(1405)-N(7))-methyltransferase
- EC
- 2.1.1.179
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 28 · 3 records with a druggable one
Structures
5 records of Q33DX5 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6CN0 | 2.95 Angstrom Crystal Structure of 16S rRNA Methylase from Proteus mirabilis | x-ray diffraction | A, B, C, D | SO4, CL | 14 (best 0.84) |
| 6CN0 | 2.95 ångström crystal structure of 16S rRNA methylase from proteus mirabilis | x-ray diffraction | A, B, C, D | SO4, CL | — |
| 6PQB | Crystal structure of aminoglycoside-resistance methyltransferase RmtC bound to… | x-ray diffraction | A, B, C, D | SAH | 13 (best 0.86) |
| 6PQB | Crystal structure of aminoglycoside-resistance methyltransferase rmtc bound to… | x-ray diffraction | A, B, C, D | — | — |
| Q33DX5 | AlphaFold monomer V2.0 prediction for 16S rRNA (GUANINE(1405)-N(7))-methyltransferase (Q33DX5) | predicted | A | — | 1 (best 0.60) |
Ligands
Experiment against prediction
- 6PQB chain A against the predicted model Q33DX5: TM-score 0.97, RMSD 1.07 Å
- 6PQB chain B against the predicted model Q33DX5: TM-score 0.97, RMSD 1.08 Å
- 6CN0 chain A against the predicted model Q33DX5: TM-score 0.97, RMSD 1.17 Å
- 6CN0 chain A against the predicted model Q33DX5: TM-score 0.97, RMSD 1.17 Å
- 6PQB chain A against the predicted model Q33DX5: TM-score 0.97, RMSD 1.07 Å
- 6PQB chain B against the predicted model Q33DX5: TM-score 0.97, RMSD 1.08 Å
- 6CN0 chain D against the predicted model Q33DX5: TM-score 0.96, RMSD 1.34 Å
- 6CN0 chain D against the predicted model Q33DX5: TM-score 0.96, RMSD 1.34 Å
- 6PQB chain C against the predicted model Q33DX5: TM-score 0.96, RMSD 1.28 Å
- 6PQB chain C against the predicted model Q33DX5: TM-score 0.96, RMSD 1.28 Å
Elsewhere
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