UniProt Q32P28
Prolyl 3-hydroxylase 1 (Q32P28)
Prolyl 3-hydroxylase 1 (UniProt Q32P28), EC 1.14.11.7: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 35 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q32P28
- Protein
- Prolyl 3-hydroxylase 1
- EC
- 1.14.11.7
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 35 · 3 records with a druggable one
Structures
3 records of Q32P28 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8K0F | Human collagen prolyl processing enzyme complex, P3H1/CRTAP/PPIB heterotrimer, in its apo state | electron microscopy | A | NAG, FE | 14 (best 0.81) |
| 8KC9 | Human collagen prolyl processing enzyme complex, P3H1/CRTAP/PPIB heterotrimer, bound to cyclosporin… | electron microscopy | A | NAG, FE | 15 (best 0.80) |
| Q32P28 | AlphaFold monomer V2.0 prediction for prolyl 3-hydroxylase 1 (Q32P28) | predicted | A | — | 6 (best 0.72) |
Ligands
Experiment against prediction
- 8K0F chain A against the predicted model Q32P28: TM-score 0.65, RMSD 3.75 Å
- 8KC9 chain A against the predicted model Q32P28: TM-score 0.64, RMSD 3.84 Å
Elsewhere
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